Tan Lab | DSigDB

Gene Set: D1 - Approved - BECLOMETHASONE

Collection

D1 : Approved

Chemical Name

BECLOMETHASONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
408.916 g/mol	3	5	2.165	True

Structure

InChI

InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChIKey

NBMKJKDGKREAPL-DVTGEIKXSA-N

Links

Gene (11 / 29)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Ratio Potency (uM)	uM	0.012	AR	-	GI(Protien) :
PubChem	Potency	uM	0.012	AR	-	GI(Protien) :
PubChem	Potency	uM	0.013	AR	-	GI(Protien) :
PubChem	Potency	uM	0.047	AR	-	GI(Protien) :
PubChem		uM		CFTR	-	GI(Protien) :
PubChem		uM		CYP1A2		GI(Protien) :
PubChem		uM		CYP2C19		GI(Protien) :
PubChem		uM		CYP2C9		GI(Protien) :
PubChem		uM		CYP2D6		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem	Potency	uM	1.000	HIF1A	-	GI(Protien) :
PubChem		uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	0.015	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.015	NFE2L2	-	GI(Protien) :
PubChem	IC50	uM	0.008	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.033	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	0.035	NR3C1	-	GI(Protien) :
PubChem		uM		NR3C1	-	GI(Protien) :
ChEMBL	Potency	nM	12.600	AR	-	Target : CHEMBL1871
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	1000.000	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	14.600	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	35.500	NR3C1	-	Target : CHEMBL2034

Download gene sets

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