Tan Lab | DSigDB

Gene Set: D1 - Approved - BUMETANIDE

Collection

D1 : Approved

Chemical Name

BUMETANIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
364.416 g/mol	3	7	4.8906	True

Structure

InChI

InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)

InChIKey

Links

Gene (19 / 24)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem		uM		BAP1	-	GI(Protien) :
PubChem		uM		CA1		GI(Protien) :
PubChem		uM		CA12		GI(Protien) :
PubChem		uM		CA14		GI(Protien) :
PubChem		uM		CA2		GI(Protien) :
PubChem		uM		CA4		GI(Protien) :
PubChem		uM		CA5A		GI(Protien) :
PubChem		uM		CA5B		GI(Protien) :
PubChem		uM		CA6		GI(Protien) :
PubChem		uM		CA7		GI(Protien) :
PubChem		uM		CA9		GI(Protien) :
PubChem		uM		CFTR	-	GI(Protien) :
PubChem		uM		CFTR	-	GI(Protien) :
PubChem		uM		MAP4K2	-	GI(Protien) :
PubChem	Potency	uM	5.805	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	6.513	NFE2L2	-	GI(Protien) :
PubChem		uM		SLC12A1	-	GI(Protien) :
PubChem		uM		SLC12A5	-	GI(Protien) :
PubChem		uM		SLC12A5	-	GI(Protien) :
ChEMBL	Potency	nM	15848.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	25118.900	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	5804.800	NFE2L2	-	Target : CHEMBL1075094

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