Tan Lab | DSigDB

Gene Set: D1 - Approved - AMILORIDE

Collection

D1 : Approved

Chemical Name

AMILORIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
229.627 g/mol	4	8	1.271	True

Structure

InChI

InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)

InChIKey

XSDQTOBWRPYKKA-UHFFFAOYSA-N

Links

Gene (7 / 12)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Ki	uM	3.280	ADORA2A		GI(Protien) :
PubChem	Ki	uM	11.600	ADORA2A		GI(Protien) :
PubChem	Ki	uM	12.000	ADORA2A		GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem	IC50	uM	3.909	MAOA	-	GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	33.492	TP53	-	GI(Protien) :
ChEMBL	Potency	nM	33587.500	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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