Tan Lab | DSigDB

Gene Set: D1 - Approved - AMILORIDE HYDROCHLORIDE

Collection

D1 : Approved

Chemical Name

AMILORIDE HYDROCHLORIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
266.088 g/mol	5	8	2.073	True

Structure

InChI

InChI=1S/C6H8ClN7O.ClH/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;/h(H4,8,9,13)(H4,10,11,14,15);1H

InChIKey

ACHKKGDWZVCSNH-UHFFFAOYSA-N

Links

Gene (9 / 16)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	AhR Potency (uM)	uM	65.148	AHR	-	GI(Protien) :
PubChem		uM		NAE1	-	GI(Protien) :
PubChem	Potency	uM	25.264	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	33.050	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	42.163	NFE2L2	-	GI(Protien) :
PubChem	DR_IC50uM_Run1	uM	6.629	PLK1	-	GI(Protien) :
PubChem	DR_IC50uM_Run1	uM	6.885	PRKD1	-	GI(Protien) :
PubChem		uM		PRKD1	-	GI(Protien) :
PubChem		uM		PRKD1	-	GI(Protien) :
PubChem		uM		PTBP1	-	GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
PubChem	Potency	uM	0.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.458	TDP1	-	GI(Protien) :
PubChem		uM		UBE2M	-	GI(Protien) :

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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