Tan Lab | DSigDB

Gene Set: D1 - Approved - ERYTHROMYCIN

Collection

D1 : Approved

Chemical Name

ERYTHROMYCIN

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
733.927 g/mol	5	14	1.7856	False(2/4)

Structure

InChI

InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

InChIKey

ULGZDMOVFRHVEP-RWJQBGPGSA-N

Links

Gene (15 / 29)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem		uM		ACP1	-	GI(Protien) :
PubChem	Kd	uM	12.000	ALB		GI(Protien) :
PubChem		uM		CFTR	-	GI(Protien) :
PubChem		uM		CYP1A2		GI(Protien) :
PubChem		uM		CYP2C19		GI(Protien) :
PubChem		uM		CYP2C9		GI(Protien) :
PubChem		uM		CYP2D6		GI(Protien) :
PubChem	IC50	uM	0.190	CYP3A4		GI(Protien) :
PubChem	IC50	uM	1.900	CYP3A4		GI(Protien) :
PubChem		uM		DNMT1	-	GI(Protien) :
PubChem	Potency	uM	10.591	ESR1	-	GI(Protien) :
PubChem		uM		F2RL1		GI(Protien) :
PubChem		uM		F2RL1		GI(Protien) :
PubChem		uM		F2RL1		GI(Protien) :
PubChem		uM		F2RL1		GI(Protien) :
PubChem	IC50	uM	0.039	KCNH2		GI(Protien) :
PubChem	EC50	uM	0.050	MLNR		GI(Protien) :
PubChem	EC50	uM	0.050	MLNR		GI(Protien) :
PubChem	EC50	uM	0.631	MLNR		GI(Protien) :
PubChem	Potency	uM	21.192	PLK1	-	GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		F2RL1	-	Target : CHEMBL5963
ChEMBL	Inhibition	-		F2RL1	-	Target : CHEMBL5963
ChEMBL	Inhibition	-		F2RL1	-	Target : CHEMBL5963
ChEMBL	Inhibition	-		F2RL1	-	Target : CHEMBL5963

Download gene sets

gmt, text, Detailed text