Tan Lab | DSigDB

Gene Set: D1 - Approved - BETAMETHASONE

Collection

D1 : Approved

Chemical Name

BETAMETHASONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
392.461 g/mol	3	5	1.8957	True

Structure

InChI

InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChIKey

UREBDLICKHMUKA-DVTGEIKXSA-N

Links

Gene (7 / 26)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	AhR Potency (uM)	uM	24.337	AHR	-	GI(Protien) :
PubChem	Potency	uM	0.001	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.002	AR	-	GI(Protien) :
PubChem	Potency	uM	0.005	AR	-	GI(Protien) :
PubChem	Potency	uM	0.010	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.011	AR	-	GI(Protien) :
PubChem	Potency	uM	0.011	AR	-	GI(Protien) :
PubChem	Potency	uM	0.038	AR	-	GI(Protien) :
PubChem		uM		CFTR	-	GI(Protien) :
PubChem		uM		CFTR	-	GI(Protien) :
PubChem		uM		GALR3	-	GI(Protien) :
PubChem		uM		GALR3	-	GI(Protien) :
PubChem		uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	0.005	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.016	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.004	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.005	NR3C1	-	GI(Protien) :
PubChem	IC50	uM	0.008	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.025	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	0.089	NR3C1	-	GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
ChEMBL	Potency	nM	10.000	AR	-	Target : CHEMBL1871
ChEMBL	Potency	nM	16.400	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	89.100	NR3C1	-	Target : CHEMBL2034

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