Tan Lab | DSigDB

Gene Set: D1 - Approved - HYDRALAZINE HYDROCHLORIDE

Collection

D1 : Approved

Chemical Name

HYDRALAZINE HYDROCHLORIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
196.637 g/mol	3	4	2.4907	True

Structure

InChI

InChI=1S/C8H8N4.ClH/c9-11-8-7-4-2-1-3-6(7)5-10-12-8;/h1-5H,9H2,(H,11,12);1H

InChIKey

Links

Gene (14 / 24)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	8.635	AHR	-	GI(Protien) :
PubChem	Potency	uM	9.688	AHR	-	GI(Protien) :
PubChem	Potency	uM	1.800	ATAD5	-	GI(Protien) :
PubChem	ATAD5 Potency (uM)	uM	1.800	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	31.623	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	8.635	ESR1	-	GI(Protien) :
PubChem		uM		GAPDH	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	54.941	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	4.856	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	48.966	NR1H4	-	GI(Protien) :
PubChem		uM		NR1H4	-	GI(Protien) :
PubChem	Potency	uM	38.895	PPARD	-	GI(Protien) :
PubChem	Potency	uM	6.310	SMN2	-	GI(Protien) :
PubChem	Potency	uM	12.589	SMN2	-	GI(Protien) :
PubChem	Potency	uM	7.943	TP53	-	GI(Protien) :
PubChem	Potency	uM	10.000	TP53	-	GI(Protien) :
PubChem		uM		VDR	-	GI(Protien) :
ChEMBL	Potency	nM	31622.800	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	19952.600	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	6309.600	SMN2	-	Target : CHEMBL1293232
ChEMBL	Potency	nM	12589.300	SMN2	-	Target : CHEMBL1293232
ChEMBL	Potency	nM	7943.300	TP53	-	Target : CHEMBL4096
ChEMBL	Potency	nM	10000.000	TP53	-	Target : CHEMBL4096

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