Tan Lab | DSigDB

Gene Set: D1 - Approved - METHYLPREDNISOLONE

Collection

D1 : Approved

Chemical Name

METHYLPREDNISOLONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
374.471 g/mol	3	5	1.8036	True

Structure

InChI

InChI=1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1

InChIKey

VHRSUDSXCMQTMA-PJHHCJLFSA-N

Links

Gene (5 / 19)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.019	AR	-	GI(Protien) :
PubChem	Potency	uM	0.032	AR	-	GI(Protien) :
PubChem	Potency	uM	0.039	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.047	AR	-	GI(Protien) :
PubChem	Potency	uM	0.049	AR	-	GI(Protien) :
PubChem	Potency	uM	0.051	AR	-	GI(Protien) :
PubChem		uM		CFTR	-	GI(Protien) :
PubChem	Potency	uM	0.026	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.033	NFE2L2	-	GI(Protien) :
PubChem	IC50	uM	0.011	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.021	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	0.031	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.038	NR3C1	-	GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
PubChem		uM		NR3C1	-	GI(Protien) :
ChEMBL	Potency	nM	25.900	NFE2L2	-	Target : CHEMBL1075094

Download gene sets

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