Tan Lab | DSigDB

Gene Set: D1 - Approved - CHLORPROMAZINE HYDROCHLORIDE

Collection

D1 : Approved

Chemical Name

CHLORPROMAZINE HYDROCHLORIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
355.325 g/mol	1	2	5.7614	False(3/4)

Structure

InChI

InChI=1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

InChIKey

FBSMERQALIEGJT-UHFFFAOYSA-N

Links

Gene (32 / 43)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		APAF1	-	GI(Protien) :
PubChem	Potency	uM	43.641	AR	-	GI(Protien) :
PubChem	Potency	uM	39.811	BAZ2B	-	GI(Protien) :
PubChem		uM		CHRM1	-	GI(Protien) :
PubChem		uM		CHRM4	-	GI(Protien) :
PubChem		uM		CHRM5	-	GI(Protien) :
PubChem		uM		DRD1	-	GI(Protien) :
PubChem		uM		DRD1	-	GI(Protien) :
PubChem		uM		DRD2		GI(Protien) :
PubChem		uM		DRD2	-	GI(Protien) :
PubChem		uM		DRD3		GI(Protien) :
PubChem		uM		DRD3	-	GI(Protien) :
PubChem		uM		DRD4		GI(Protien) :
PubChem		uM		GFER	-	GI(Protien) :
PubChem		uM		HTR1E	-	GI(Protien) :
PubChem		uM		HTR2A		GI(Protien) :
PubChem	Potency	uM	3.981	KCNH2		GI(Protien) :
PubChem	Potency	uM	3.981	KCNH2		GI(Protien) :
PubChem		uM		MAP4K2	-	GI(Protien) :
PubChem		uM		MDM2	-	GI(Protien) :
PubChem		uM		MDM4	-	GI(Protien) :
PubChem	AC50_uM	uM	16.330	MLLT3	-	GI(Protien) :
PubChem		uM		MLLT3	-	GI(Protien) :
PubChem	Potency	uM	35.481	MPHOSPH8	-	GI(Protien) :
PubChem	Potency	uM	48.966	NR1H4	-	GI(Protien) :
PubChem	Potency	uM	44.668	NR1I2	-	GI(Protien) :
PubChem	Potency	uM	12.300	PPARD	-	GI(Protien) :
PubChem		uM		PPARG	-	GI(Protien) :
PubChem		uM		PTBP1	-	GI(Protien) :
PubChem		uM		RAD52	-	GI(Protien) :
PubChem	Potency	uM	10.871	TP53	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	24.337	TP53	-	GI(Protien) :
ChEMBL	Potency	nM	39810.700	ATXN2	-	Target : CHEMBL1795085
ChEMBL	Potency	nM	39810.700	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	AC50	nM	7079.460	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	28183.800	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	70794.600	EHMT2	-	Target : CHEMBL6032
ChEMBL	AC50	nM	1013.000	GFER	-	Target : CHEMBL1741189
ChEMBL	Potency	nM	14581.000	IDH1	-	Target : CHEMBL2007625
ChEMBL	Potency	nM	3981.100	KCNH2	-	Target : CHEMBL240
ChEMBL	Potency	nM	19952.600	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	35481.300	MPHOSPH8	-	Target : CHEMBL1741210
ChEMBL	AC50	nM	25270.000	RAD52	-	Target : CHEMBL2362978

Download gene sets

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