Tan Lab | DSigDB

Gene Set: D1 - Approved - TESTOSTERONE

Collection

D1 : Approved

Chemical Name

TESTOSTERONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
288.424 g/mol	1	2	3.8792	True

Structure

InChI

InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

InChIKey

MUMGGOZAMZWBJJ-DYKIIFRCSA-N

Links

Gene (15 / 48)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		AKR1C4	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.001	AR	-	GI(Protien) :
PubChem	Potency	uM	0.002	AR	-	GI(Protien) :
PubChem	Potency	uM	0.002	AR	-	GI(Protien) :
PubChem	IC50	uM	0.003	AR		GI(Protien) :
PubChem	EC50	uM	0.003	AR		GI(Protien) :
PubChem	IC50	uM	0.004	AR		GI(Protien) :
PubChem	IC50	uM	0.005	AR		GI(Protien) :
PubChem	Potency	uM	0.007	AR	-	GI(Protien) :
PubChem		uM		AR	-	GI(Protien) :
PubChem	Km	uM	0.130	CYP19A1		GI(Protien) :
PubChem	Ki	uM	0.600	CYP19A1		GI(Protien) :
PubChem		uM		CYP19A1		GI(Protien) :
PubChem		uM		CYP1A2		GI(Protien) :
PubChem		uM		CYP2C19		GI(Protien) :
PubChem		uM		CYP2D6		GI(Protien) :
PubChem	IC50	uM	10.000	CYP3A4		GI(Protien) :
PubChem	Km	uM	20.500	CYP3A4		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem	Potency	uM	0.021	ESR1	-	GI(Protien) :
PubChem	Potency	uM	6.870	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	10.475	ESR1	-	GI(Protien) :
PubChem	Potency	uM	12.589	ESR1	-	GI(Protien) :
PubChem		uM		ESR1		GI(Protien) :
PubChem	EC50	uM	18.300	GPBAR1		GI(Protien) :
PubChem	Ratio Potency (uM)	uM	21.536	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	2.438	NR3C1	-	GI(Protien) :
PubChem	IC50	uM	3.206	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	7.080	NR3C1	-	GI(Protien) :
PubChem		uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	26.603	RORC	-	GI(Protien) :
PubChem	Potency	uM	12.589	RXRA	-	GI(Protien) :
PubChem	Kd	uM	0.001	SHBG		GI(Protien) :
PubChem	IC50	uM	0.014	SHBG		GI(Protien) :
PubChem	IC50	uM		TDP1		GI(Protien) :
ChEMBL	Potency	nM	1.600	AR	-	Target : CHEMBL1871
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Activity	-		ESR1	-	Target : CHEMBL206
ChEMBL	Potency	nM	12589.300	ESR1	-	Target : CHEMBL206
ChEMBL	Potency	nM	7079.500	NR3C1	-	Target : CHEMBL2034
ChEMBL	Potency	nM	26603.200	RORC	-	Target : CHEMBL1741186
ChEMBL	Potency	nM	12589.300	RXRA	-	Target : CHEMBL2061
ChEMBL	Inhibition	-		TDP1	-	Target : CHEMBL1075138

Download gene sets

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