Tan Lab | DSigDB

Gene Set: D1 - Approved - EPINEPHRINE

Collection

D1 : Approved

Chemical Name

EPINEPHRINE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
183.204 g/mol	4	4	0.7415	True

Structure

InChI

InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1

InChIKey

UCTWMZQNUQWSLP-VIFPVBQESA-N

Links

Gene (27 / 60)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ADRA1A	-	GI(Protien) :
PubChem		uM		ADRA1B	-	GI(Protien) :
PubChem	IC50	uM	0.449	ADRA1D	-	GI(Protien) :
PubChem		uM		ADRA1D	-	GI(Protien) :
PubChem	EC50	uM	0.300	ADRA2A		GI(Protien) :
PubChem	IC50	uM	0.737	ADRA2A	-	GI(Protien) :
PubChem		uM		ADRA2A	-	GI(Protien) :
PubChem	EC50	uM	0.300	ADRA2B		GI(Protien) :
PubChem	IC50	uM	0.869	ADRA2B	-	GI(Protien) :
PubChem		uM		ADRA2B	-	GI(Protien) :
PubChem	EC50	uM	0.300	ADRA2C		GI(Protien) :
PubChem	IC50	uM	2.449	ADRA2C	-	GI(Protien) :
PubChem		uM		ADRA2C	-	GI(Protien) :
PubChem		uM		ADRB1	-	GI(Protien) :
PubChem	IC50	uM	0.284	ADRB2	-	GI(Protien) :
PubChem	Kd	uM	0.630	ADRB2		GI(Protien) :
PubChem	Kd	uM	0.631	ADRB2		GI(Protien) :
PubChem		uM		ADRB2	-	GI(Protien) :
PubChem	EC50	uM	0.031	ADRB3		GI(Protien) :
PubChem	EC50	uM	0.049	ADRB3		GI(Protien) :
PubChem		uM		ADRB3	-	GI(Protien) :
PubChem		uM		CA1		GI(Protien) :
PubChem		uM		CA14		GI(Protien) :
PubChem		uM		CA4		GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	0.164	DRD1	-	GI(Protien) :
PubChem	Potency	uM	2.512	DRD1	-	GI(Protien) :
PubChem	Potency	uM	10.621	FEN1	-	GI(Protien) :
PubChem	Potency	uM	10.621	FEN1	-	GI(Protien) :
PubChem		uM		GAPDH	-	GI(Protien) :
PubChem	Potency	uM	1.585	HIF1A	-	GI(Protien) :
PubChem	Potency	uM	7.943	MAPT	-	GI(Protien) :
PubChem	Potency	uM	12.589	MAPT	-	GI(Protien) :
PubChem	Potency	uM	14.125	MAPT	-	GI(Protien) :
PubChem	Potency	uM	26.122	MTOR	-	GI(Protien) :
PubChem	Potency	uM	48.558	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	1.995	POLK	-	GI(Protien) :
PubChem	Potency	uM	2.668	POLK	-	GI(Protien) :
PubChem	Potency	uM	7.080	POLK	-	GI(Protien) :
PubChem	Potency	uM	8.414	TDP1	-	GI(Protien) :
PubChem	Potency	uM	11.886	TDP1	-	GI(Protien) :
PubChem	Potency	uM	31.623	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	8912.500	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	3548.100	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	7943.300	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	2511.900	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	163.600	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	1584.900	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	794.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	7079.500	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	14125.400	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	7943.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	12589.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	26121.600	MTOR	-	Target : CHEMBL2842
ChEMBL	Potency	nM	48557.700	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	1995.300	POLK	-	Target : CHEMBL5365
ChEMBL	Potency	nM	2667.900	POLK	-	Target : CHEMBL5365
ChEMBL	Potency	nM	7079.500	POLK	-	Target : CHEMBL5365
ChEMBL	Potency	nM	17782.800	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	31622.800	VDR	-	Target : CHEMBL1977

Download gene sets

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