Tan Lab | DSigDB

Gene Set: D1 - Approved - RESERPINE

Collection

D1 : Approved

Chemical Name

RESERPINE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
608.679 g/mol	1	10	4.109	False(3/4)

Structure

InChI

InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1

InChIKey

QEVHRUUCFGRFIF-MDEJGZGSSA-N

Links

Gene (25 / 59)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	3.020	ABCB1		GI(Protien) :
PubChem	IC50	uM	3.236	ABCB1		GI(Protien) :
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem	IC50	uM	26.303	ABCG2		GI(Protien) :
PubChem	AhR Potency (uM)	uM	12.542	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	28.726	AHR	-	GI(Protien) :
PubChem	Potency	uM	39.663	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	68.450	AHR	-	GI(Protien) :
PubChem	Potency	uM	68.450	AHR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	9.671	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	38.492	AR	-	GI(Protien) :
PubChem	Potency	uM	61.006	AR	-	GI(Protien) :
PubChem	Potency	uM	10.000	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	11.577	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	28.184	BAZ2B	-	GI(Protien) :
PubChem	Potency	uM	39.811	CBX1	-	GI(Protien) :
PubChem	Potency	uM	16.785	CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	27.250	CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	56.025	CYP19A1	-	GI(Protien) :
PubChem		uM		CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	0.848	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.197	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.974	ESR1	-	GI(Protien) :
PubChem	Potency	uM	15.089	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	20.336	ESR1	-	GI(Protien) :
PubChem	Potency	uM	21.132	ESR1	-	GI(Protien) :
PubChem	Potency	uM	56.025	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	56.025	ESR1	-	GI(Protien) :
PubChem	Potency	uM	10.000	GLS	-	GI(Protien) :
PubChem	Potency	uM	11.220	GMNN	-	GI(Protien) :
PubChem	Potency	uM	29.855	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.794	KCNH2		GI(Protien) :
PubChem	Potency	uM	0.794	KCNH2		GI(Protien) :
PubChem	Potency	uM	5.012	KCNH2		GI(Protien) :
PubChem	Potency	uM	5.012	KCNH2		GI(Protien) :
PubChem	Potency	uM	11.582	KPNB1	-	GI(Protien) :
PubChem	Potency	uM	19.953	MPHOSPH8	-	GI(Protien) :
PubChem	Potency	uM	10.000	NR1I2	-	GI(Protien) :
PubChem	Potency	uM	35.481	NR1I2	-	GI(Protien) :
PubChem		uM		NR3C1	-	GI(Protien) :
PubChem	IC50	uM	4.152	OPRM1	-	GI(Protien) :
PubChem	Potency	uM	11.582	RAN	-	GI(Protien) :
PubChem		uM		SLC18A2	-	GI(Protien) :
PubChem	Potency	uM	11.582	SNUPN	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :
PubChem	Potency	uM	31.623	THPO	-	GI(Protien) :
ChEMBL	Potency	nM	11577.400	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	10000.000	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	28183.800	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	39810.700	CBX1	-	Target : CHEMBL1741193
ChEMBL	Potency	nM	22387.200	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	11220.200	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	29855.400	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	794.300	KCNH2	-	Target : CHEMBL240
ChEMBL	Potency	nM	5011.900	KCNH2	-	Target : CHEMBL240
ChEMBL	Potency	nM	56234.100	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	12589.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	19952.600	MPHOSPH8	-	Target : CHEMBL1741210
ChEMBL	Potency	nM	31622.800	THPO	-	Target : CHEMBL1293256

Download gene sets

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