Tan Lab | DSigDB

Gene Set: D1 - Approved - HYDROCORTISONE

Collection

D1 : Approved

Chemical Name

HYDROCORTISONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
362.46 g/mol	3	5	1.7816	True

Structure

InChI

InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChIKey

JYGXADMDTFJGBT-VWUMJDOOSA-N

Links

Gene (10 / 38)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Ratio Potency (uM)	uM	0.010	AR	-	GI(Protien) :
PubChem	Potency	uM	0.014	AR	-	GI(Protien) :
PubChem	Potency	uM	0.021	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.023	AR	-	GI(Protien) :
PubChem	Potency	uM	0.028	AR	-	GI(Protien) :
PubChem	Potency	uM	0.069	AR	-	GI(Protien) :
PubChem	Potency	uM	0.119	AR	-	GI(Protien) :
PubChem		uM		CFTR	-	GI(Protien) :
PubChem	Potency	uM	3.758	ESR1	-	GI(Protien) :
PubChem	Potency	uM	0.200	HIF1A	-	GI(Protien) :
PubChem		uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	0.029	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.073	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.164	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.206	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.291	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.014	NFKB1	-	GI(Protien) :
PubChem	IC50	uM	0.026	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.039	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	0.067	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.079	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	0.079	NR3C1	-	GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
PubChem		uM		NR3C1		GI(Protien) :
PubChem		uM		NR3C1	-	GI(Protien) :
PubChem	Kd	uM	0.631	SHBG		GI(Protien) :
ChEMBL	Potency	nM	14.100	AR	-	Target : CHEMBL1871
ChEMBL	Potency	nM	199.500	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	163.600	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	29.100	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	73.100	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	14.100	NFKB1	-	Target : CHEMBL3251
ChEMBL	Potency	nM	79.400	NR3C1	-	Target : CHEMBL2034
ChEMBL	Activity	-		NR3C1	-	Target : CHEMBL2034

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