Tan Lab | DSigDB

Gene Set: D1 - Approved - TRIFLUPROMAZINE

Collection

D1 : Approved

Chemical Name

TRIFLUPROMAZINE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
352.417 g/mol	0	2	5.3248	False(3/4)

Structure

InChI

InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3

InChIKey

Links

Gene (5 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	0.398	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	0.794	CYP2D6	-	GI(Protien) :
PubChem		uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	1.259	DRD1	-	GI(Protien) :
PubChem		uM		DRD2		GI(Protien) :
PubChem		uM		DRD2		GI(Protien) :
PubChem		uM		DRD2		GI(Protien) :
PubChem	Potency	uM	12.589	TP53	-	GI(Protien) :
ChEMBL	AC50	nM	1584.890	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	794.330	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	794.300	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	398.100	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	398.110	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	794.330	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	1258.900	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	12589.300	TP53	-	Target : CHEMBL4096

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