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Gene Set: D1 - Approved - TRIAMTERENE

Collection D1 : Approved
Chemical Name TRIAMTERENE
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
253.263 g/mol 3 7 2.577 True
Structure
InChI InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)
InChIKey FNYLWPVRPXGIIP-UHFFFAOYSA-N
Links

Gene (29 / 76)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
PubChem AhR Potency (uM)uM11.515AHR-GI(Protien) :
PubChem AhR Potency (uM)uM29.814AHR-GI(Protien) :
PubChem PotencyuM21.314AR-GI(Protien) :
PubChem PotencyuM44.668AR-GI(Protien) :
PubChem PotencyuM48.972AR-GI(Protien) :
PubChem PotencyuM49.512AR-GI(Protien) :
PubChem ATAD5 Potency (uM)uM66.007ATAD5-GI(Protien) :
PubChem ATAD5 Potency (uM)uM68.039ATAD5-GI(Protien) :
PubChem IC50uM3.663CASP1-GI(Protien) :
PubChem IC50uMCBFB-GI(Protien) :
PubChem IC50uM7.413CTSG-GI(Protien) :
PubChem uMCYP1A2-GI(Protien) :
PubChem uMCYP1A2-GI(Protien) :
PubChem IC50uM10.000CYP2D6-GI(Protien) :
PubChem PotencyuM35.481ESR1-GI(Protien) :
PubChem PotencyuM68.590ESR1-GI(Protien) :
PubChem PotencyuM39.811GAA-GI(Protien) :
PubChem PotencyuM10.000HIF1A-GI(Protien) :
PubChem PotencyuM24.544HSPB1-GI(Protien) :
PubChem PotencyuM29.847HSPB1-GI(Protien) :
PubChem PotencyuM49.512HSPB1-GI(Protien) :
PubChem PotencyuM2.311IDH1-GI(Protien) :
PubChem IC50uM4.613JAK2-GI(Protien) :
PubChem uMJAK2-GI(Protien) :
PubChem uMJAK2-GI(Protien) :
PubChem uMKLK7-GI(Protien) :
PubChem uMKLK7-GI(Protien) :
PubChem PotencyuM23.708NFE2L2-GI(Protien) :
PubChem PotencyuM30.638NFE2L2-GI(Protien) :
PubChem PotencyuM30.981NFE2L2-GI(Protien) :
PubChem PotencyuM33.492NFE2L2-GI(Protien) :
PubChem PotencyuM54.483NFE2L2-GI(Protien) :
PubChem PotencyuM21.130NR1H4-GI(Protien) :
PubChem PotencyuM49.512NR1H4-GI(Protien) :
PubChem PotencyuM48.972NR3C1-GI(Protien) :
PubChem PotencyuM23.708PPARD-GI(Protien) :
PubChem PotencyuM24.544PPARD-GI(Protien) :
PubChem PotencyuM23.915PPARG-GI(Protien) :
PubChem IC50uMRUNX1-GI(Protien) :
PubChem uMSCNN1AGI(Protien) :
PubChem uMSCNN1BGI(Protien) :
PubChem uMSCNN1GGI(Protien) :
PubChem PotencyuM2.060TDP1-GI(Protien) :
PubChem PotencyuM6.684TDP1-GI(Protien) :
PubChem PotencyuM8.200TDP1-GI(Protien) :
PubChem PotencyuM14.963TDP1-GI(Protien) :
PubChem PotencyuM15.849TDP1-GI(Protien) :
PubChem PotencyuM17.783TDP1-GI(Protien) :
PubChem PotencyuM18.356TDP1-GI(Protien) :
PubChem PotencyuM22.387THRB-GI(Protien) :
PubChem uMTNFRSF10B-GI(Protien) :
PubChem uMTNFRSF10B-GI(Protien) :
PubChem uMTNFRSF10B-GI(Protien) :
PubChem PotencyuM12.589TP53-GI(Protien) :
PubChem PotencyuM15.527TP53-GI(Protien) :
PubChem PotencyuM19.953TP53-GI(Protien) :
PubChem PotencyuM26.603TP53-GI(Protien) :
PubChem Ratio Potency (uM)uM27.612TP53-GI(Protien) :
PubChem PotencyuM34.376TP53-GI(Protien) :
PubChem Ratio Potency (uM)uM44.970TP53-GI(Protien) :
ChEMBLPotencynM44668.400AR
-Target : CHEMBL1871
ChEMBLAC50nM5011.870CYP1A2
-Target : CHEMBL3356
ChEMBLPotencynM35481.300ESR1
-Target : CHEMBL206
ChEMBLPotencynM39810.700GAA
-Target : CHEMBL2608
ChEMBLPotencynM10000.000HIF1A
-Target : CHEMBL4261
ChEMBLPotencynM3162.300HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM5011.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM1258.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM7943.300HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM2310.900IDH1
-Target : CHEMBL2007625
ChEMBLIC50nM4613.000JAK2
-Target : CHEMBL2971
ChEMBLPotencynM54482.700NFE2L2
-Target : CHEMBL1075094
ChEMBLPotencynM33491.500NFE2L2
-Target : CHEMBL1075094
ChEMBLPotencynM22387.200THRB
-Target : CHEMBL1947
ChEMBLPotencynM19952.600TP53
-Target : CHEMBL4096
ChEMBLPotencynM12589.300TP53
-Target : CHEMBL4096
Download gene sets gmt, text, Detailed text
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