Tan Lab | DSigDB

Gene Set: D1 - Approved - TRAZODONE

Collection

D1 : Approved

Chemical Name

TRAZODONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
371.864 g/mol	0	6	2.3646	True

Structure

InChI

InChI=1S/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2

InChIKey

Links

Gene (14 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	0.265	ADRA1D	-	GI(Protien) :
PubChem	IC50	uM	0.909	ADRA2A	-	GI(Protien) :
PubChem	IC50	uM	0.389	ADRA2B	-	GI(Protien) :
PubChem	IC50	uM	1.942	ADRA2C	-	GI(Protien) :
PubChem	Potency	uM	11.220	DRD1	-	GI(Protien) :
PubChem	IC50	uM	3.743	DRD3	-	GI(Protien) :
PubChem	IC50	uM	0.361	HRH1	-	GI(Protien) :
PubChem	IC50	uM	0.020	HTR2A	-	GI(Protien) :
PubChem		uM		HTR2A		GI(Protien) :
PubChem	IC50	uM	0.107	HTR2B	-	GI(Protien) :
PubChem		uM		HTR2B		GI(Protien) :
PubChem		uM		HTR2B		GI(Protien) :
PubChem	IC50	uM	0.091	HTR2C	-	GI(Protien) :
PubChem		uM		HTR2C		GI(Protien) :
PubChem	Potency	uM	11.220	KAT2A	-	GI(Protien) :
PubChem	IC50	uM	2.203	SIGMAR1	-	GI(Protien) :
PubChem	IC50	uM	0.192	SLC6A4	-	GI(Protien) :
ChEMBL	Potency	nM	11220.200	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	15848.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	11220.200	KAT2A	-	Target : CHEMBL5501

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