Tan Lab | DSigDB

Gene Set: D1 - Approved - THIABENDAZOLE

Collection

D1 : Approved

Chemical Name

THIABENDAZOLE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
201.248 g/mol	1	3	2.6864	True

Structure

InChI

InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)

InChIKey

Links

Gene (10 / 31)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	AhR Potency (uM)	uM	5.011	AHR	-	GI(Protien) :
PubChem	Potency	uM	8.413	AHR	-	GI(Protien) :
PubChem	Potency	uM	12.589	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	13.685	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	14.867	AHR	-	GI(Protien) :
PubChem	Potency	uM	15.449	AHR	-	GI(Protien) :
PubChem	Potency	uM	27.306	AHR	-	GI(Protien) :
PubChem	ATAD5 Potency (uM)	uM	16.785	ATAD5	-	GI(Protien) :
PubChem	ATAD5 Potency (uM)	uM	34.376	ATAD5	-	GI(Protien) :
PubChem	ATAD5 Potency (uM)	uM	43.541	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	11.220	BRCA1	-	GI(Protien) :
PubChem	IC50	uM	0.800	CYP1A2	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	9.688	ESR1	-	GI(Protien) :
PubChem	Potency	uM	16.785	ESR1	-	GI(Protien) :
PubChem	Potency	uM	24.485	ESR1	-	GI(Protien) :
PubChem		uM		FKBP1A	-	GI(Protien) :
PubChem		uM		INS	-	GI(Protien) :
PubChem	EC50	uM	3.400	METAP1		GI(Protien) :
PubChem	IC50	uM	47.800	METAP1		GI(Protien) :
PubChem	IC50	uM	44.700	METAP2		GI(Protien) :
PubChem	Potency	uM	8.912	SMN2	-	GI(Protien) :
PubChem	Potency	uM	12.589	SMN2	-	GI(Protien) :
PubChem	Potency	uM	25.119	SMN2	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	AHR	-	Target : CHEMBL3201
ChEMBL	Potency	nM	11220.200	BRCA1	-	Target : CHEMBL5990
ChEMBL	AC50	nM	125.890	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	12589.300	SMN2	-	Target : CHEMBL1293232
ChEMBL	Potency	nM	25118.900	SMN2	-	Target : CHEMBL1293232
ChEMBL	Potency	nM	8912.500	SMN2	-	Target : CHEMBL1293232

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