Tan Lab | DSigDB

Gene Set: D1 - Approved - TERAZOSIN

Collection

D1 : Approved

Chemical Name

TERAZOSIN

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
387.433 g/mol	1	9	1.6409	True

Structure

InChI

InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)/t14-/m0/s1

InChIKey

VCKUSRYTPJJLNI-AWEZNQCLSA-N

Links

Gene (15 / 28)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Ki	uM	0.007	ADRA1A		GI(Protien) :
PubChem	Ki	uM	0.002	ADRA1B		GI(Protien) :
PubChem	Ki	uM	0.004	ADRA1D		GI(Protien) :
PubChem	IC50	uM	0.017	ADRA1D	-	GI(Protien) :
PubChem	Ki	uM	3.702	ADRA2A		GI(Protien) :
PubChem	IC50	uM	13.832	ADRA2A	-	GI(Protien) :
PubChem	Ki	uM	0.418	ADRA2B		GI(Protien) :
PubChem	IC50	uM	0.428	ADRA2B	-	GI(Protien) :
PubChem	IC50	uM	6.042	ADRA2C	-	GI(Protien) :
PubChem		uM		CYP1A2		GI(Protien) :
PubChem		uM		CYP2C19		GI(Protien) :
PubChem		uM		CYP2C9		GI(Protien) :
PubChem		uM		CYP2D6		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem	Potency	uM	4.467	HTT	-	GI(Protien) :
PubChem	IC50	uM	17.783	KCNH2		GI(Protien) :
PubChem	IC50	uM	23.700	SLC22A1		GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
PubChem		uM		SLC5A7	-	GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	4466.800	HTT	-	Target : CHEMBL5514

Download gene sets

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