Tan Lab | DSigDB

Gene Set: D1 - Approved - SULFAPHENAZOLE

Collection

D1 : Approved

Chemical Name

SULFAPHENAZOLE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
314.362 g/mol	2	6	3.9903	True

Structure

InChI

InChI=1S/C15H14N4O2S/c16-12-6-8-14(9-7-12)22(20,21)18-15-10-11-17-19(15)13-4-2-1-3-5-13/h1-11,18H,16H2

InChIKey

QWCJHSGMANYXCW-UHFFFAOYSA-N

Links

Gene (7 / 38)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		CYP1A2		GI(Protien) :
PubChem		uM		CYP2C19		GI(Protien) :
PubChem	Potency	uM	0.050	CYP2C9	-	GI(Protien) :
PubChem	IC50	uM	0.200	CYP2C9	-	GI(Protien) :
PubChem	IC50	uM	0.250	CYP2C9		GI(Protien) :
PubChem	IC50	uM	0.250	CYP2C9		GI(Protien) :
PubChem	IC50	uM	0.318	CYP2C9		GI(Protien) :
PubChem	IC50	uM	0.318	CYP2C9		GI(Protien) :
PubChem	IC50	uM	0.318	CYP2C9		GI(Protien) :
PubChem	IC50	uM	0.350	CYP2C9		GI(Protien) :
PubChem	Potency	uM	0.398	CYP2C9	-	GI(Protien) :
PubChem		uM		CYP2C9	-	GI(Protien) :
PubChem		uM		CYP2C9		GI(Protien) :
PubChem		uM		CYP2D6		GI(Protien) :
PubChem	Potency	uM	0.126	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	3.162	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP3A4	-	GI(Protien) :
PubChem		uM		CYP3A4	-	GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem	Potency	uM	7.080	NFKB1	-	GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	398.100	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	50.100	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	398.110	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	50.120	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	125.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	7943.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	3162.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	3162.280	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	7943.280	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	10000.000	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	7079.500	NFKB1	-	Target : CHEMBL3251

Download gene sets

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