Tan Lab | DSigDB

Gene Set: D1 - Approved - ROPINIROLE

Collection

D1 : Approved

Chemical Name

ROPINIROLE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
260.375 g/mol	1	3	2.9837	True

Structure

InChI

InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19)

InChIKey

Links

Gene (5 / 21)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Potency	uM	3.162	CYP2D6	-	GI(Protien) :
PubChem		uM		CYP2D6	-	GI(Protien) :
PubChem	Ki	uM	0.007	DRD2		GI(Protien) :
PubChem	EC50	uM	0.083	DRD2		GI(Protien) :
PubChem	EC50	uM	0.304	DRD2		GI(Protien) :
PubChem	EC50	uM	0.304	DRD2		GI(Protien) :
PubChem	EC50	uM	0.304	DRD2		GI(Protien) :
PubChem	Ki	uM	0.692	DRD2		GI(Protien) :
PubChem	EC50	uM	0.004	DRD3		GI(Protien) :
PubChem	EC50	uM	0.010	DRD3		GI(Protien) :
PubChem	EC50	uM	0.010	DRD3		GI(Protien) :
PubChem	Ki	uM	0.019	DRD3		GI(Protien) :
PubChem	EC50	uM	0.019	DRD3		GI(Protien) :
PubChem	Ki	uM	0.036	DRD3		GI(Protien) :
PubChem	Ki	uM	0.061	DRD3		GI(Protien) :
PubChem		uM		DRD3	-	GI(Protien) :
PubChem		uM		DRD3	-	GI(Protien) :
PubChem	Ki	uM	1.706	HTR1A		GI(Protien) :
ChEMBL	AC50	nM	3162.280	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	3162.300	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	10000.000	KCNH2	-	Target : CHEMBL240

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