Tan Lab | DSigDB

Gene Set: D1 - Approved - PHENYLBUTAZONE

Collection

D1 : Approved

Chemical Name

PHENYLBUTAZONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
308.374 g/mol	0	4	3.9178	True

Structure

InChI

InChI=1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3

InChIKey

Links

Gene (16 / 28)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ALB		GI(Protien) :
PubChem		uM		CYP1A2		GI(Protien) :
PubChem		uM		CYP2C19		GI(Protien) :
PubChem		uM		CYP2C9		GI(Protien) :
PubChem		uM		CYP2D6		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem		uM		ESR1	-	GI(Protien) :
PubChem		uM		ESR2	-	GI(Protien) :
PubChem	IC50_MICROM	uM	5.300	FPR1	-	GI(Protien) :
PubChem		uM		FPR1	-	GI(Protien) :
PubChem		uM		FPR1	-	GI(Protien) :
PubChem		uM		FPR1	-	GI(Protien) :
PubChem		uM		ITGA4	-	GI(Protien) :
PubChem		uM		ITGA4	-	GI(Protien) :
PubChem		uM		MCL1	-	GI(Protien) :
PubChem	Potency	uM	7.943	NR1I2	-	GI(Protien) :
PubChem	Potency	uM	44.668	NR1I2	-	GI(Protien) :
PubChem		uM		PTGS1	-	GI(Protien) :
PubChem		uM		PTGS2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		TP53	-	GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	10000.000	EHMT2	-	Target : CHEMBL6032

Download gene sets