Tan Lab | DSigDB

Gene Set: D1 - Approved - OMEPRAZOLE

Collection

D1 : Approved

Chemical Name

OMEPRAZOLE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
345.416 g/mol	1	5	3.7654	True

Structure

InChI

InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m0/s1

InChIKey

SUBDBMMJDZJVOS-DEOSSOPVSA-N

Links

Gene (28 / 67)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	21.132	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	22.264	AHR	-	GI(Protien) :
PubChem	Potency	uM	47.966	AHR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	33.492	AR	-	GI(Protien) :
PubChem		uM		ATP4A		GI(Protien) :
PubChem		uM		ATP4A		GI(Protien) :
PubChem		uM		ATP4A		GI(Protien) :
PubChem		uM		ATP4B		GI(Protien) :
PubChem		uM		ATP4B		GI(Protien) :
PubChem		uM		ATP4B		GI(Protien) :
PubChem	Potency	uM	31.623	BAZ2B	-	GI(Protien) :
PubChem	Potency	uM	14.125	CBX1	-	GI(Protien) :
PubChem		uM		CHRM4	-	GI(Protien) :
PubChem		uM		CYP1A2		GI(Protien) :
PubChem	Potency	uM	2.512	CYP2C19	-	GI(Protien) :
PubChem		uM		CYP2C19	-	GI(Protien) :
PubChem		uM		CYP2C9		GI(Protien) :
PubChem		uM		CYP2D6		GI(Protien) :
PubChem	Potency	uM	10.000	CYP3A4	-	GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem		uM		CYP3A4	-	GI(Protien) :
PubChem		uM		GFER	-	GI(Protien) :
PubChem	Potency	uM	28.184	HPGD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	30.529	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	48.386	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	22.387	MAPT	-	GI(Protien) :
PubChem	Potency	uM	31.623	MAPT	-	GI(Protien) :
PubChem	IC50	uM	3.145	MCL1	-	GI(Protien) :
PubChem		uM		MCL1	-	GI(Protien) :
PubChem	IC50	uM		MPI	-	GI(Protien) :
PubChem	IC50	uM		MPI	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	12.520	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	16.784	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	17.019	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	20.334	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	27.306	NFE2L2	-	GI(Protien) :
PubChem		uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	23.778	PLK1	-	GI(Protien) :
PubChem		uM		PPARG	-	GI(Protien) :
PubChem		uM		TRHR	-	GI(Protien) :
PubChem	Potency	uM	2.668	VDR	-	GI(Protien) :
PubChem	Potency	uM	39.811	VDR	-	GI(Protien) :
PubChem	Potency	uM	89.125	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	31622.800	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	14125.400	CBX1	-	Target : CHEMBL1741193
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	2511.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	2511.890	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	10000.000	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	10000.000	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	1412.500	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	1584.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	28183.800	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	28183.800	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	25118.900	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	11220.200	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	31622.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	22387.200	MAPT	-	Target : CHEMBL1293224
ChEMBL	IC50	nM	3144.810	MCL1	-	Target : CHEMBL4361
ChEMBL	Potency	nM	27306.000	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	39810.700	VDR	-	Target : CHEMBL1977
ChEMBL	Potency	nM	89125.100	VDR	-	Target : CHEMBL1977
ChEMBL	Potency	nM	2667.900	VDR	-	Target : CHEMBL1977

Download gene sets

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