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Gene Set: D1 - Approved - NISOLDIPINE

Collection D1 : Approved
Chemical Name NISOLDIPINE
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
388.414 g/mol 1 5 4.0538 True
Structure
InChI InChI=1S/C20H24N2O6/c1-11(2)10-28-20(24)17-13(4)21-12(3)16(19(23)27-5)18(17)14-8-6-7-9-15(14)22(25)26/h6-9,11,18,21H,10H2,1-5H3/t18-/m1/s1
InChIKey VKQFCGNPDRICFG-GOSISDBHSA-N
Links

Gene (41 / 80)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
PubChem uMABHD5-GI(Protien) :
PubChem uMABHD5-GI(Protien) :
PubChem IC50uM4.058ADORA2A-GI(Protien) :
PubChem IC50uM7.120ADORA3-GI(Protien) :
PubChem AhR Potency (uM)uM3.857AHR-GI(Protien) :
PubChem PotencyuM9.439AHR-GI(Protien) :
PubChem AhR Potency (uM)uMAHR-GI(Protien) :
PubChem PotencyuM16.930AR-GI(Protien) :
PubChem Ratio Potency (uM)uM19.739AR-GI(Protien) :
PubChem AR Potency (uM)uM29.849AR-GI(Protien) :
PubChem PotencyuM29.849AR-GI(Protien) :
PubChem PotencyuM61.131AR-GI(Protien) :
PubChem uMCACNA1C-GI(Protien) :
PubChem uMCACNA1D-GI(Protien) :
PubChem uMCACNA1F-GI(Protien) :
PubChem uMCACNA1S-GI(Protien) :
PubChem PotencyuM15.849CBX1-GI(Protien) :
PubChem uMCFTR-GI(Protien) :
PubChem uMCFTR-GI(Protien) :
PubChem PotencyuM33.492CYP19A1-GI(Protien) :
PubChem PotencyuM61.131CYP19A1-GI(Protien) :
PubChem IC50uM1.000CYP1A2-GI(Protien) :
PubChem uMCYP1A2GI(Protien) :
PubChem uMCYP2C19GI(Protien) :
PubChem uMCYP2C9GI(Protien) :
PubChem uMCYP2D6GI(Protien) :
PubChem uMCYP3A4GI(Protien) :
PubChem uMCYP3A4GI(Protien) :
PubChem Ratio Potency (uM)uM24.541ESR1-GI(Protien) :
PubChem PotencyuM54.941ESR1-GI(Protien) :
PubChem PotencyuM26.609GMNN-GI(Protien) :
PubChem uMHNF4A-GI(Protien) :
PubChem Ratio Potency (uM)uM24.541HSPB1-GI(Protien) :
PubChem PotencyuM16.360IDH1-GI(Protien) :
PubChem uMIL1B-GI(Protien) :
PubChem uMKCNH2-GI(Protien) :
PubChem uMKCNH2-GI(Protien) :
PubChem uMKCNQ1-GI(Protien) :
PubChem uMMDM2-GI(Protien) :
PubChem uMMDM2-GI(Protien) :
PubChem uMMDM4-GI(Protien) :
PubChem uMMDM4-GI(Protien) :
PubChem AC50_uMuM17.980MLLT3-GI(Protien) :
PubChem uMMLLT3-GI(Protien) :
PubChem uMMRGPRX1-GI(Protien) :
PubChem PotencyuM16.360NFE2L2-GI(Protien) :
PubChem PotencyuM23.708NFE2L2-GI(Protien) :
PubChem PotencyuM24.541NR3C1-GI(Protien) :
PubChem uMPLIN5-GI(Protien) :
PubChem uMPLIN5-GI(Protien) :
PubChem PotencyuM18.888PLK1-GI(Protien) :
PubChem uMPRMT1-GI(Protien) :
PubChem PotencyuM17.783SMAD3-GI(Protien) :
PubChem PotencyuM35.481TARDBP-GI(Protien) :
PubChem PotencyuM5.173TDP1-GI(Protien) :
PubChem PotencyuM6.513TDP1-GI(Protien) :
PubChem PotencyuM8.414TDP1-GI(Protien) :
PubChem PotencyuM8.414TDP1-GI(Protien) :
PubChem PotencyuM26.603TP53-GI(Protien) :
PubChem Ratio Potency (uM)uM29.849TP53-GI(Protien) :
PubChem PotencyuM5.623VDR-GI(Protien) :
PubChem PotencyuM8.912VDR-GI(Protien) :
PubChem PotencyuM14.125VDR-GI(Protien) :
ChEMBLPotencynM15848.900CBX1
-Target : CHEMBL1741193
ChEMBLInhibition-CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM11220.200EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM26608.600GMNN
-Target : CHEMBL1293278
ChEMBLPotencynM16360.100IDH1
-Target : CHEMBL2007625
ChEMBLPotencynM19952.600KDM4A
-Target : CHEMBL5896
ChEMBLPotencynM16360.100NFE2L2
-Target : CHEMBL1075094
ChEMBLPotencynM17782.800SMAD3
-Target : CHEMBL1293258
ChEMBLPotencynM35481.300TARDBP
-Target : CHEMBL2362981
ChEMBLPotencynM5623.400VDR
-Target : CHEMBL1977
ChEMBLPotencynM8912.500VDR
-Target : CHEMBL1977
ChEMBLPotencynM14125.400VDR
-Target : CHEMBL1977
Download gene sets gmt, text, Detailed text
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