Tan Lab | DSigDB

Gene Set: D1 - Approved - NABUMETONE

Collection

D1 : Approved

Chemical Name

NABUMETONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
228.286 g/mol	0	2	3.37	True

Structure

InChI

InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3

InChIKey

Links

Gene (12 / 21)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Potency	uM	3.201	AHR	-	GI(Protien) :
PubChem	Potency	uM	4.522	ATAD5	-	GI(Protien) :
PubChem	ATAD5 Potency (uM)	uM	4.699	ATAD5	-	GI(Protien) :
PubChem	IC50	uM	5.000	CYP1A2	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	1.274	ESR1	-	GI(Protien) :
PubChem		uM		ESR1	-	GI(Protien) :
PubChem	IC50	uM	0.998	MAOA	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	24.636	NFE2L2	-	GI(Protien) :
PubChem		uM		NR0B1	-	GI(Protien) :
PubChem		uM		NR0B1	-	GI(Protien) :
PubChem		uM		NR5A1	-	GI(Protien) :
PubChem		uM		PTGS2	-	GI(Protien) :
PubChem	Potency	uM	28.184	RAPGEF4	-	GI(Protien) :
PubChem	IC50	uM	1.868	SLC6A2	-	GI(Protien) :
PubChem	Potency	uM	11.220	SMN2	-	GI(Protien) :
PubChem	Potency	uM	12.589	SMN2	-	GI(Protien) :
ChEMBL	AC50	nM	398.110	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	11220.200	SMN2	-	Target : CHEMBL1293232
ChEMBL	Potency	nM	12589.300	SMN2	-	Target : CHEMBL1293232

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