Tan Lab | DSigDB

Gene Set: D1 - Approved - METOLAZONE

Collection

D1 : Approved

Chemical Name

METOLAZONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
365.835 g/mol	2	6	4.6982	True

Structure

InChI

InChI=1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8,10,19H,1-2H3,(H2,18,22,23)/t10-/m0/s1

InChIKey

AQCHWTWZEMGIFD-JTQLQIEISA-N

Links

Gene (12 / 13)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABCB1	-	GI(Protien) :
PubChem		uM		CA12		GI(Protien) :
PubChem		uM		CA14		GI(Protien) :
PubChem		uM		CA2		GI(Protien) :
PubChem		uM		CA4		GI(Protien) :
PubChem		uM		CA5A		GI(Protien) :
PubChem		uM		CA5B		GI(Protien) :
PubChem		uM		CA6		GI(Protien) :
PubChem	Ki	uM	0.002	CA7		GI(Protien) :
PubChem		uM		CA7		GI(Protien) :
PubChem		uM		CA9		GI(Protien) :
PubChem		uM		SLC12A3	-	GI(Protien) :
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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