Tan Lab | DSigDB

Gene Set: D1 - Approved - AMRINONE

Collection

D1 : Approved

Chemical Name

AMRINONE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
187.198 g/mol	2	3	1.6003	True

Structure

InChI

InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)

InChIKey

RNLQIBCLLYYYFJ-UHFFFAOYSA-N

Links

Gene (29 / 54)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem		uM		ABHD5	-	GI(Protien) :
PubChem		uM		ABHD5	-	GI(Protien) :
PubChem	Potency	uM	11.220	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	12.589	ALOX15	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP2C19	-	GI(Protien) :
PubChem		uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	19.953	CYP3A4	-	GI(Protien) :
PubChem		uM		DLD	-	GI(Protien) :
PubChem		uM		GAPDH	-	GI(Protien) :
PubChem		uM		GSTO1	-	GI(Protien) :
PubChem	Potency	uM	3.981	HIF1A	-	GI(Protien) :
PubChem	Potency	uM	1.413	MAPT	-	GI(Protien) :
PubChem	Potency	uM	1.995	MAPT	-	GI(Protien) :
PubChem	Potency	uM	3.548	MAPT	-	GI(Protien) :
PubChem	Potency	uM	4.467	MAPT	-	GI(Protien) :
PubChem	Potency	uM	10.000	MAPT	-	GI(Protien) :
PubChem		uM		MAPT	-	GI(Protien) :
PubChem		uM		MAPT	-	GI(Protien) :
PubChem	IC50	uM		MPI	-	GI(Protien) :
PubChem	IC50	uM	16.000	PDE3A		GI(Protien) :
PubChem	IC50	uM	16.000	PDE3B		GI(Protien) :
PubChem	Potency	uM		PIP4K2A	-	GI(Protien) :
PubChem		uM		PLIN1	-	GI(Protien) :
PubChem		uM		PLIN5	-	GI(Protien) :
PubChem	Potency	uM	29.935	PLK1	-	GI(Protien) :
PubChem	Potency	uM	10.000	POLI	-	GI(Protien) :
PubChem		uM		PRMT1	-	GI(Protien) :
PubChem		uM		S100A4	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :
PubChem	Potency	uM	14.125	THRB	-	GI(Protien) :
PubChem	Potency	uM	39.811	USP1	-	GI(Protien) :
PubChem		uM		VCP	-	GI(Protien) :
PubChem	Potency	uM	19.953	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	11220.200	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	12589.300	ALOX15	-	Target : CHEMBL2903
ChEMBL	AC50	nM	15848.900	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	5011.870	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	5011.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	19952.600	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	5623.400	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	44668.400	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	3981.100	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	10000.000	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	1122.000	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	1412.500	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	3548.100	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	4466.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	1995.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	10000.000	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	10000.000	POLI	-	Target : CHEMBL5391
ChEMBL	Potency	nM	14125.400	THRB	-	Target : CHEMBL1947
ChEMBL	Potency	nM	19952.600	VDR	-	Target : CHEMBL1977

Download gene sets

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