Tan Lab | DSigDB

Gene Set: D1 - Approved - PHENELZINE

Collection

D1 : Approved

Chemical Name

PHENELZINE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
136.194 g/mol	2	2	1.7836	True

Structure

InChI

InChI=1S/C8H12N2/c9-10-7-6-8-4-2-1-3-5-8/h1-5,10H,6-7,9H2

InChIKey

RMUCZJUITONUFY-UHFFFAOYSA-N

Links

Gene (9 / 36)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	0.020	AOC3		GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	0.316	CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	0.794	CYP2C19	-	GI(Protien) :
PubChem	IC50	uM	0.800	CYP2C19	-	GI(Protien) :
PubChem		uM		CYP2C19	-	GI(Protien) :
PubChem	IC50	uM	4.000	CYP2C9	-	GI(Protien) :
PubChem	IC50	uM	1.000	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	2.512	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	6.310	CYP2D6	-	GI(Protien) :
PubChem		uM		CYP2D6	-	GI(Protien) :
PubChem	IC50	uM	2.000	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	3.162	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP3A4	-	GI(Protien) :
PubChem		uM		CYP3A4		GI(Protien) :
PubChem		uM		CYP3A4	-	GI(Protien) :
PubChem	IC50	uM	0.146	MAOA	-	GI(Protien) :
PubChem	Potency	uM	14.125	RAB9A	-	GI(Protien) :
ChEMBL	AC50	nM	3162.280	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1000.000	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	316.200	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	794.300	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	794.330	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	316.230	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	2511.890	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	6309.600	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	2511.900	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	6309.570	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	7943.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	3162.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	3162.280	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	7943.280	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	18887.600	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	14125.400	RAB9A	-	Target : CHEMBL1293294

Download gene sets

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