Tan Lab | DSigDB

Gene Set: D1 - Approved - GEMFIBROZIL

Collection

D1 : Approved

Chemical Name

GEMFIBROZIL

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
250.333 g/mol	1	3	3.5732	True

Structure

InChI

InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)

InChIKey

Links

Gene (14 / 22)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Potency	uM	48.904	AHR	-	GI(Protien) :
PubChem		uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	6.310	CYP2C9	-	GI(Protien) :
PubChem	IC50	uM	9.600	CYP2C9		GI(Protien) :
PubChem		uM		CYP2C9	-	GI(Protien) :
PubChem		uM		NR1H2	-	GI(Protien) :
PubChem		uM		NR2F1	-	GI(Protien) :
PubChem		uM		NR5A1	-	GI(Protien) :
PubChem		uM		NR5A1	-	GI(Protien) :
PubChem		uM		NR5A2	-	GI(Protien) :
PubChem		uM		PPARA		GI(Protien) :
PubChem		uM		PPARA	-	GI(Protien) :
PubChem		uM		RARA	-	GI(Protien) :
PubChem		uM		RARA	-	GI(Protien) :
PubChem		uM		RARB	-	GI(Protien) :
PubChem		uM		RARG	-	GI(Protien) :
PubChem		uM		RORA	-	GI(Protien) :
PubChem		uM		RXRA	-	GI(Protien) :
ChEMBL	Potency	nM	6309.600	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	6309.570	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Activity	-		JUN	-	Target : CHEMBL4977
ChEMBL	Activity	-		PPARA	-	Target : CHEMBL239

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