Tan Lab | DSigDB

Gene Set: D1 - Approved - 5-FLUOROURACIL

Collection

D1 : Approved

Chemical Name

5-FLUOROURACIL

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
130.077 g/mol	2	2	-0.7977	True

Structure

InChI

InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)

InChIKey

Links

Gene (8 / 24)

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Source	Type	Unit	Value	Gene	PMID	Other
PubChem	ATAD5 Potency (uM)	uM	3.944	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	7.498	ATAD5	-	GI(Protien) :
PubChem	ATAD5 Potency (uM)	uM	7.498	ATAD5	-	GI(Protien) :
PubChem	ATAD5 Potency (uM)	uM	10.054	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	10.054	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	12.589	HBB	-	GI(Protien) :
PubChem		uM		JAK2	-	GI(Protien) :
PubChem		uM		NLRP1	-	GI(Protien) :
PubChem		uM		PTBP1	-	GI(Protien) :
PubChem	Potency	uM	14.963	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :
PubChem	Potency	uM	18.356	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.570	TP53	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	2.792	TP53	-	GI(Protien) :
PubChem	Potency	uM	3.567	TP53	-	GI(Protien) :
PubChem	Potency	uM	3.981	TP53	-	GI(Protien) :
PubChem	Potency	uM	4.216	TP53	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	4.216	TP53	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	4.322	TP53	-	GI(Protien) :
PubChem		uM		TYMS	-	GI(Protien) :
PubChem		uM		TYMS		GI(Protien) :
ChEMBL	Potency	nM	12589.300	HBB	-	Target : CHEMBL4331
ChEMBL	Potency	nM	3981.100	TP53	-	Target : CHEMBL4096
ChEMBL	Activity	-		TYMS	-	Target : CHEMBL1952

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