Tan Lab | DSigDB

Gene Set: D1 - Approved - OXYTETRACYCLINE HYDROCHLORIDE

Collection

D1 : Approved

Chemical Name

OXYTETRACYCLINE HYDROCHLORIDE

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
496.895 g/mol	8	11	0.1021	False(2/4)

Structure

InChI

InChI=1S/C22H24N2O9.ClH/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31);1H/t12?,13?,14-,17-,21+,22-;/m0./s1

InChIKey

SVDOODSCHVSYEK-WOYDFFIASA-N

Links

Gene (8 / 14)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Potency	uM	28.184	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	35.481	ESR1	-	GI(Protien) :
PubChem	Potency	uM	3.548	GLS	-	GI(Protien) :
PubChem	Potency	uM	7.080	HPGD	-	GI(Protien) :
PubChem	Potency	uM	3.359	POLK	-	GI(Protien) :
PubChem	Potency	uM	18.837	TDP1	-	GI(Protien) :
PubChem	Potency	uM	50.119	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	28183.800	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	35481.300	ESR1	-	Target : CHEMBL206
ChEMBL	Potency	nM	3548.100	GLS	-	Target : CHEMBL2146302
ChEMBL	Potency	nM	7079.500	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	6309.600	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	3358.700	POLK	-	Target : CHEMBL5365
ChEMBL	Potency	nM	50118.700	VDR	-	Target : CHEMBL1977

Download gene sets

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