Tan Lab | DSigDB

Gene Set: D1 - Approved - DOXAZOSIN

Collection

D1 : Approved

Chemical Name

DOXAZOSIN

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
451.475 g/mol	1	10	2.3019	True

Structure

InChI

InChI=1S/C23H25N5O5/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26)/t20-/m1/s1

InChIKey

RUZYUOTYCVRMRZ-HXUWFJFHSA-N

Links

Gene (14 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	Ki	uM	0.001	ADRA1A		GI(Protien) :
PubChem	Ki	uM	0.003	ADRA1A		GI(Protien) :
PubChem	Ki	uM	0.001	ADRA1B		GI(Protien) :
PubChem	Ki	uM	0.001	ADRA1B		GI(Protien) :
PubChem	Ki	uM	0.001	ADRA1D		GI(Protien) :
PubChem	Ki	uM	0.001	ADRA1D		GI(Protien) :
PubChem	IC50	uM	0.003	ADRA1D	-	GI(Protien) :
PubChem	Ki	uM	0.729	ADRA2A		GI(Protien) :
PubChem	Ki	uM	0.280	ADRA2C		GI(Protien) :
PubChem	IC50	uM	2.748	ADRB2	-	GI(Protien) :
PubChem	Potency	uM	23.100	ATAD5	-	GI(Protien) :
PubChem	IC50	uM	0.368	HTR2B	-	GI(Protien) :
PubChem	IC50	uM	0.544	HTR2C	-	GI(Protien) :
PubChem	IC50	uM	0.589	KCNH2		GI(Protien) :
PubChem	IC50	uM	2.216	KCNH2	-	GI(Protien) :
PubChem	IC50	uM	5.749	MMP1	-	GI(Protien) :
PubChem	Potency	uM	11.668	MTOR	-	GI(Protien) :
PubChem	IC50	uM	0.188	SLC6A3	-	GI(Protien) :
PubChem	IC50	uM	2.688	SLC6A4	-	GI(Protien) :
ChEMBL	Potency	nM	23099.900	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	11668.100	MTOR	-	Target : CHEMBL2842

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