Tan Lab | DSigDB

Gene Set: D1 - Approved - GUANABENZ

Collection

D1 : Approved

Chemical Name

GUANABENZ

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Approved	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
231.082 g/mol	2	4	3.0013	True

Structure

InChI

InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14)/b13-4+

InChIKey

WDZVGELJXXEGPV-YIXHJXPBSA-N

Links

Gene (11 / 17)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
PubChem	IC50	uM	0.472	ADRA1D	-	GI(Protien) :
PubChem	IC50	uM	0.041	ADRA2A	-	GI(Protien) :
PubChem	IC50	uM	0.149	ADRA2B	-	GI(Protien) :
PubChem	IC50	uM	1.106	ADRA2C	-	GI(Protien) :
PubChem	IC50	uM	0.392	HTR2A	-	GI(Protien) :
PubChem	IC50	uM	0.097	HTR2B	-	GI(Protien) :
PubChem	IC50	uM	0.204	HTR2C	-	GI(Protien) :
PubChem	IC50	uM	1.787	MAOA	-	GI(Protien) :
PubChem		uM		MAP3K3	-	GI(Protien) :
PubChem	Ki	uM	0.035	NISCH		GI(Protien) :
PubChem	IC50	uM	1.173	TAAR1	-	GI(Protien) :
PubChem	EC50	uM	3.327	TAAR1	-	GI(Protien) :
PubChem		uM		TAAR1	-	GI(Protien) :
PubChem		uM		TAAR1	-	GI(Protien) :
PubChem		uM		TAAR1	-	GI(Protien) :
ChEMBL	IC50	nM	1173.000	TAAR1	-	Target : CHEMBL5857
ChEMBL	EC50	nM	3327.000	TAAR1	-	Target : CHEMBL5857

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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