Drug	Gene	Type	Source
3-Hydroxyestra-1,3,5(10)-triene-16,17-dione	AKR1A1	Text_Mining(increases(reduction))	CTD
3-Hydroxyestra-1,3,5(10)-triene-16,17-dione	AKR1B1	Text_Mining(increases(reduction))	CTD
3-Hydroxyestra-1,3,5(10)-triene-16,17-dione	AKR7A2	Text_Mining(increases(reduction))	CTD
3-Hydroxyestra-1,3,5(10)-triene-16,17-dione	ESR2	Text_Mining(affects(binding))	CTD