Drug	Gene	Type	Source
topotecan	ABCB1	Text_Mining(decreases(activity))	CTD
topotecan	ABCB1	Text_Mining(decreases(export))	CTD
topotecan	ABCB1	Text_Mining(increases(expression))	CTD
topotecan	ABCC2	Text_Mining(decreases(activity))	CTD
topotecan	ABCC2	Text_Mining(decreases(export))	CTD
topotecan	ABCC2	Text_Mining(increases(expression))	CTD
topotecan	ABCD3	Text_Mining(affects(response to substance))	CTD
topotecan	ABCG2	Text_Mining(affects(export))	CTD
topotecan	ABCG2	Text_Mining(affects(transport))	CTD
topotecan	ABCG2	Text_Mining(decreases(response to substance))	CTD
topotecan	ABCG2	Text_Mining(increases(export))	CTD
topotecan	ABCG2	Text_Mining(increases(response to substance))	CTD
topotecan	ABCG2	Text_Mining(increases(transport))	CTD
topotecan	ABCG2	Text_Mining(decreases(activity))	CTD
topotecan	ABCG2	Text_Mining(decreases(export))	CTD
topotecan	ABCG2	Text_Mining(increases(reaction))	CTD
topotecan	ABCG2	Text_Mining(increases(expression))	CTD
topotecan	ACAT2	Text_Mining(affects(response to substance))	CTD
topotecan	ACSL3	Text_Mining(affects(response to substance))	CTD
topotecan	ACTG2	Text_Mining(affects(response to substance))	CTD
topotecan	ADAMTS1	Text_Mining(affects(response to substance))	CTD
topotecan	ADD3	Text_Mining(affects(response to substance))	CTD
topotecan	AIM1	Text_Mining(affects(response to substance))	CTD
topotecan	AKT3	Text_Mining(affects(response to substance))	CTD
topotecan	ALAD	Text_Mining(affects(response to substance))	CTD
topotecan	ANKRD10	Text_Mining(affects(response to substance))	CTD
topotecan	ANP32A	Text_Mining(affects(response to substance))	CTD
topotecan	AOX1	Text_Mining(affects(response to substance))	CTD
topotecan	AP5M1	Text_Mining(affects(response to substance))	CTD
topotecan	APOBEC3C	Text_Mining(affects(response to substance))	CTD
topotecan	ARGLU1	Text_Mining(affects(response to substance))	CTD
topotecan	ASS1	Text_Mining(affects(response to substance))	CTD
topotecan	AUTS2	Text_Mining(affects(response to substance))	CTD
topotecan	BCKDHA	Text_Mining(affects(response to substance))	CTD
topotecan	BCL2	Text_Mining(decreases(expression))	CTD
topotecan	BCL2L12	Text_Mining(decreases(expression))	CTD
topotecan	BID	Text_Mining(affects(response to substance))	CTD
topotecan	BIRC2	Text_Mining(affects(response to substance))	CTD
topotecan	BIRC5	Text_Mining(affects(cotreatment))	CTD
topotecan	BIRC5	Text_Mining(decreases(reaction))	CTD
topotecan	BIRC5	Text_Mining(increases(degradation))	CTD
topotecan	BOP1	Text_Mining(affects(response to substance))	CTD
topotecan	BORA	Text_Mining(affects(response to substance))	CTD
topotecan	C11ORF49	Text_Mining(affects(response to substance))	CTD
topotecan	CABYR	Text_Mining(affects(response to substance))	CTD
topotecan	CAMK1	Text_Mining(affects(response to substance))	CTD
topotecan	CAMSAP2	Text_Mining(affects(response to substance))	CTD
topotecan	CASP2	Text_Mining(decreases(reaction))	CTD
topotecan	CASP2	Text_Mining(increases(cleavage))	CTD
topotecan	CASP2	Text_Mining(increases(reaction))	CTD
topotecan	CASP3	Text_Mining(affects(cotreatment))	CTD
topotecan	CASP3	Text_Mining(increases(activity))	CTD
topotecan	CASP3	Text_Mining(decreases(reaction))	CTD
topotecan	CASP6	Text_Mining(affects(response to substance))	CTD
topotecan	CASP7	Text_Mining(affects(cotreatment))	CTD
topotecan	CASP7	Text_Mining(increases(activity))	CTD
topotecan	CASP8	Text_Mining(affects(cotreatment))	CTD
topotecan	CASP8	Text_Mining(increases(activity))	CTD
topotecan	CASP8	Text_Mining(decreases(reaction))	CTD
topotecan	CAT	Text_Mining(affects(response to substance))	CTD
topotecan	CAT	Text_Mining(increases(expression))	CTD
topotecan	CCNB2	Text_Mining(affects(response to substance))	CTD
topotecan	CCNE1	Text_Mining(decreases(expression))	CTD
topotecan	CCNF	Text_Mining(affects(response to substance))	CTD
topotecan	CCNG2	Text_Mining(affects(response to substance))	CTD
topotecan	CD24	Text_Mining(affects(response to substance))	CTD
topotecan	CDH1	Text_Mining(affects(response to substance))	CTD
topotecan	CDKN1C	Text_Mining(affects(response to substance))	CTD
topotecan	CENPU	Text_Mining(affects(response to substance))	CTD
topotecan	CITED2	Text_Mining(affects(response to substance))	CTD
topotecan	CKAP2	Text_Mining(affects(response to substance))	CTD
topotecan	CLCN3	Text_Mining(affects(response to substance))	CTD
topotecan	COL6A1	Text_Mining(affects(response to substance))	CTD
topotecan	COL6A2	Text_Mining(affects(response to substance))	CTD
topotecan	COX17	Text_Mining(affects(response to substance))	CTD
topotecan	CSF2RA	Text_Mining(affects(response to substance))	CTD
topotecan	CSTF2T	Text_Mining(affects(response to substance))	CTD
topotecan	CTNNB1	Text_Mining(decreases(reaction))	CTD
topotecan	CTNNB1	Text_Mining(increases(cleavage))	CTD
topotecan	CTSL	Text_Mining(affects(response to substance))	CTD
topotecan	CUL4A	Text_Mining(affects(response to substance))	CTD
topotecan	CYB5A	Text_Mining(affects(response to substance))	CTD
topotecan	DDIT4	Text_Mining(affects(response to substance))	CTD
topotecan	DKK3	Text_Mining(affects(response to substance))	CTD
topotecan	DLC1	Text_Mining(affects(response to substance))	CTD
topotecan	DRAP1	Text_Mining(affects(response to substance))	CTD
topotecan	DSE	Text_Mining(affects(response to substance))	CTD
topotecan	DSP	Text_Mining(affects(response to substance))	CTD
topotecan	DUSP3	Text_Mining(affects(response to substance))	CTD
topotecan	DZIP1	Text_Mining(affects(response to substance))	CTD
topotecan	EGFR	Text_Mining(decreases(expression))	CTD
topotecan	EGFR	Text_Mining(decreases(phosphorylation))	CTD
topotecan	EGFR	Text_Mining(decreases(activity))	CTD
topotecan	EGFR	Text_Mining(decreases(response to substance))	CTD
topotecan	EIF5A	Text_Mining(affects(response to substance))	CTD
topotecan	ELL3	Text_Mining(affects(response to substance))	CTD
topotecan	ENOPH1	Text_Mining(affects(response to substance))	CTD
topotecan	EPCAM	Text_Mining(affects(response to substance))	CTD
topotecan	ERBB3	Text_Mining(affects(response to substance))	CTD
topotecan	ESRP1	Text_Mining(affects(response to substance))	CTD
topotecan	EVA1B	Text_Mining(affects(response to substance))	CTD
topotecan	EZH2	Text_Mining(affects(response to substance))	CTD
topotecan	FAM111A	Text_Mining(affects(response to substance))	CTD
topotecan	FAM129A	Text_Mining(affects(response to substance))	CTD
topotecan	FAM171A1	Text_Mining(affects(response to substance))	CTD
topotecan	FANCI	Text_Mining(affects(response to substance))	CTD
topotecan	FANCL	Text_Mining(affects(response to substance))	CTD
topotecan	FAS	Text_Mining(decreases(expression))	CTD
topotecan	FDFT1	Text_Mining(affects(response to substance))	CTD
topotecan	FGD1	Text_Mining(affects(response to substance))	CTD
topotecan	FGF2	Text_Mining(affects(response to substance))	CTD
topotecan	FHL1	Text_Mining(affects(response to substance))	CTD
topotecan	FIG4	Text_Mining(affects(response to substance))	CTD
topotecan	FJX1	Text_Mining(affects(response to substance))	CTD
topotecan	FLNC	Text_Mining(affects(response to substance))	CTD
topotecan	FOS	Text_Mining(decreases(reaction))	CTD
topotecan	FOS	Text_Mining(increases(expression))	CTD
topotecan	FOXD1	Text_Mining(affects(response to substance))	CTD
topotecan	FRMD4A	Text_Mining(affects(response to substance))	CTD
topotecan	FTH1	Text_Mining(affects(response to substance))	CTD
topotecan	FUCA1	Text_Mining(affects(response to substance))	CTD
topotecan	GALNT1	Text_Mining(affects(response to substance))	CTD
topotecan	GALNT3	Text_Mining(affects(response to substance))	CTD
topotecan	GCA	Text_Mining(affects(response to substance))	CTD
topotecan	GCH1	Text_Mining(affects(response to substance))	CTD
topotecan	GJA1	Text_Mining(affects(response to substance))	CTD
topotecan	GMDS	Text_Mining(affects(response to substance))	CTD
topotecan	GPSM2	Text_Mining(affects(response to substance))	CTD
topotecan	GSPT2	Text_Mining(affects(response to substance))	CTD
topotecan	GTF2I	Text_Mining(affects(response to substance))	CTD
topotecan	H2AFV	Text_Mining(affects(response to substance))	CTD
topotecan	H2AFX	Text_Mining(affects(cotreatment))	CTD
topotecan	H2AFX	Text_Mining(increases(expression))	CTD
topotecan	H2AFX	Text_Mining(increases(phosphorylation))	CTD
topotecan	HADH	Text_Mining(affects(response to substance))	CTD
topotecan	HDAC9	Text_Mining(affects(response to substance))	CTD
topotecan	HIF1A	Text_Mining(affects(localization))	CTD
topotecan	HIF1A	Text_Mining(decreases(reaction))	CTD
topotecan	HIF1A	Text_Mining(affects(binding))	CTD
topotecan	HIF1A	Text_Mining(increases(reaction))	CTD
topotecan	HIF1A	Text_Mining(decreases(expression))	CTD
topotecan	HMGA1	Text_Mining(affects(response to substance))	CTD
topotecan	HMGA2	Text_Mining(affects(response to substance))	CTD
topotecan	HMGB1	Text_Mining(affects(response to substance))	CTD
topotecan	HMGB2	Text_Mining(affects(response to substance))	CTD
topotecan	HMGCS1	Text_Mining(affects(response to substance))	CTD
topotecan	HMGN3	Text_Mining(affects(response to substance))	CTD
topotecan	HN1L	Text_Mining(affects(response to substance))	CTD
topotecan	HNRNPDL	Text_Mining(affects(response to substance))	CTD
topotecan	HOXB2	Text_Mining(affects(response to substance))	CTD
topotecan	HSPA2	Text_Mining(affects(response to substance))	CTD
topotecan	HTATIP2	Text_Mining(affects(response to substance))	CTD
topotecan	IGFBP3	Text_Mining(affects(response to substance))	CTD
topotecan	IGFBP7	Text_Mining(affects(response to substance))	CTD
topotecan	IL1RAPL1	Text_Mining(affects(response to substance))	CTD
topotecan	INHBA	Text_Mining(affects(response to substance))	CTD
topotecan	INSIG1	Text_Mining(affects(response to substance))	CTD
topotecan	ISG15	Text_Mining(affects(response to substance))	CTD
topotecan	ITGA5	Text_Mining(affects(response to substance))	CTD
topotecan	JUN	Text_Mining(decreases(reaction))	CTD
topotecan	JUN	Text_Mining(increases(expression))	CTD
topotecan	JUN	Text_Mining(affects(binding))	CTD
topotecan	JUN	Text_Mining(increases(reaction))	CTD
topotecan	JUN	Text_Mining(increases(phosphorylation))	CTD
topotecan	KCNMA1	Text_Mining(affects(response to substance))	CTD
topotecan	KCTD3	Text_Mining(affects(response to substance))	CTD
topotecan	KRT19	Text_Mining(affects(response to substance))	CTD
topotecan	LAMC1	Text_Mining(affects(response to substance))	CTD
topotecan	LARP6	Text_Mining(affects(response to substance))	CTD
topotecan	LEPR	Text_Mining(affects(response to substance))	CTD
topotecan	LIMK2	Text_Mining(affects(response to substance))	CTD
topotecan	LIN7C	Text_Mining(affects(response to substance))	CTD
topotecan	LOXL2	Text_Mining(affects(response to substance))	CTD
topotecan	LTBP2	Text_Mining(affects(response to substance))	CTD
topotecan	MACF1	Text_Mining(affects(response to substance))	CTD
topotecan	MAGED1	Text_Mining(affects(response to substance))	CTD
topotecan	MBD4	Text_Mining(affects(response to substance))	CTD
topotecan	MBP	Text_Mining(affects(response to substance))	CTD
topotecan	MCTP2	Text_Mining(affects(response to substance))	CTD
topotecan	MEST	Text_Mining(affects(response to substance))	CTD
topotecan	MGMT	Text_Mining(decreases(expression))	CTD
topotecan	MKNK2	Text_Mining(affects(response to substance))	CTD
topotecan	MMP1	Text_Mining(affects(response to substance))	CTD
topotecan	MOK	Text_Mining(affects(response to substance))	CTD
topotecan	MPZL2	Text_Mining(affects(response to substance))	CTD
topotecan	MRPL57	Text_Mining(affects(response to substance))	CTD
topotecan	MSMO1	Text_Mining(affects(response to substance))	CTD
topotecan	MTOR	Text_Mining(decreases(reaction))	CTD
topotecan	MTOR	Text_Mining(increases(phosphorylation))	CTD
topotecan	MTUS1	Text_Mining(affects(response to substance))	CTD
topotecan	MYO1D	Text_Mining(affects(response to substance))	CTD
topotecan	NAB1	Text_Mining(affects(response to substance))	CTD
topotecan	NCAPH	Text_Mining(affects(response to substance))	CTD
topotecan	NMT2	Text_Mining(affects(response to substance))	CTD
topotecan	NOC3L	Text_Mining(affects(response to substance))	CTD
topotecan	NRIP3	Text_Mining(affects(response to substance))	CTD
topotecan	NSMAF	Text_Mining(affects(response to substance))	CTD
topotecan	NUDT4	Text_Mining(affects(response to substance))	CTD
topotecan	OPTN	Text_Mining(affects(response to substance))	CTD
topotecan	PCNA	Text_Mining(decreases(expression))	CTD
topotecan	PDE8A	Text_Mining(affects(response to substance))	CTD
topotecan	PDGFC	Text_Mining(affects(response to substance))	CTD
topotecan	PIN4	Text_Mining(affects(response to substance))	CTD
topotecan	FERMT2	Text_Mining(affects(response to substance))	CTD
topotecan	PLOD2	Text_Mining(affects(response to substance))	CTD
topotecan	PNMAL1	Text_Mining(affects(response to substance))	CTD
topotecan	PTPRK	Text_Mining(affects(response to substance))	CTD
topotecan	PTRF	Text_Mining(affects(response to substance))	CTD
topotecan	PTX3	Text_Mining(affects(response to substance))	CTD
topotecan	QKI	Text_Mining(affects(response to substance))	CTD
topotecan	RAB13	Text_Mining(affects(response to substance))	CTD
topotecan	RAB20	Text_Mining(affects(response to substance))	CTD
topotecan	RAB29	Text_Mining(affects(response to substance))	CTD
topotecan	RAI14	Text_Mining(affects(response to substance))	CTD
topotecan	RANBP1	Text_Mining(affects(response to substance))	CTD
topotecan	RDX	Text_Mining(affects(response to substance))	CTD
topotecan	RFTN1	Text_Mining(affects(response to substance))	CTD
topotecan	RGS20	Text_Mining(affects(response to substance))	CTD
topotecan	RIPK2	Text_Mining(affects(response to substance))	CTD
topotecan	RNF219	Text_Mining(affects(response to substance))	CTD
topotecan	RPA1	Text_Mining(affects(response to substance))	CTD
topotecan	SAP18	Text_Mining(affects(response to substance))	CTD
topotecan	SAR1A	Text_Mining(affects(response to substance))	CTD
topotecan	SATB1	Text_Mining(affects(response to substance))	CTD
topotecan	SCD	Text_Mining(affects(response to substance))	CTD
topotecan	SCRN1	Text_Mining(affects(response to substance))	CTD
topotecan	SEC14L1	Text_Mining(affects(response to substance))	CTD
topotecan	SERPINB1	Text_Mining(affects(response to substance))	CTD
topotecan	SERPINB2	Text_Mining(affects(response to substance))	CTD
topotecan	SERPINE1	Text_Mining(affects(response to substance))	CTD
topotecan	SFRP1	Text_Mining(affects(response to substance))	CTD
topotecan	SKP2	Text_Mining(affects(response to substance))	CTD
topotecan	SLC35G2	Text_Mining(affects(response to substance))	CTD
topotecan	SLC38A6	Text_Mining(affects(response to substance))	CTD
topotecan	SLC39A8	Text_Mining(affects(response to substance))	CTD
topotecan	SMARCA4	Text_Mining(affects(response to substance))	CTD
topotecan	SNAPC1	Text_Mining(affects(response to substance))	CTD
topotecan	SNRPA1	Text_Mining(affects(response to substance))	CTD
topotecan	SORL1	Text_Mining(affects(response to substance))	CTD
topotecan	SPAG9	Text_Mining(affects(response to substance))	CTD
topotecan	SPP1	Text_Mining(affects(response to substance))	CTD
topotecan	SRD5A1	Text_Mining(affects(response to substance))	CTD
topotecan	SRGN	Text_Mining(affects(response to substance))	CTD
topotecan	SRI	Text_Mining(affects(response to substance))	CTD
topotecan	ST7	Text_Mining(affects(response to substance))	CTD
topotecan	STC1	Text_Mining(affects(response to substance))	CTD
topotecan	SUV420H1	Text_Mining(affects(response to substance))	CTD
topotecan	TBC1D4	Text_Mining(affects(response to substance))	CTD
topotecan	TCF3	Text_Mining(affects(response to substance))	CTD
topotecan	TCF7L2	Text_Mining(affects(response to substance))	CTD
topotecan	TFPI	Text_Mining(affects(response to substance))	CTD
topotecan	TFPI2	Text_Mining(affects(response to substance))	CTD
topotecan	TGM2	Text_Mining(affects(response to substance))	CTD
topotecan	TIA1	Text_Mining(affects(response to substance))	CTD
topotecan	TMC6	Text_Mining(affects(response to substance))	CTD
topotecan	TMEM80	Text_Mining(affects(response to substance))	CTD
topotecan	TMEM97	Text_Mining(affects(response to substance))	CTD
topotecan	TNFAIP8	Text_Mining(affects(response to substance))	CTD
topotecan	TNFRSF6B	Text_Mining(affects(response to substance))	CTD
topotecan	TOP2A	Text_Mining(decreases(expression))	CTD
topotecan	TP53	Text_Mining(increases(activity))	CTD
topotecan	TP53	Text_Mining(increases(expression))	CTD
topotecan	TP53	Text_Mining(decreases(reaction))	CTD
topotecan	TP53	Text_Mining(increases(cleavage))	CTD
topotecan	TPK1	Text_Mining(affects(response to substance))	CTD
topotecan	TPM1	Text_Mining(affects(response to substance))	CTD
topotecan	TREX1	Text_Mining(decreases(reaction))	CTD
topotecan	TREX1	Text_Mining(increases(expression))	CTD
topotecan	TREX1	Text_Mining(affects(binding))	CTD
topotecan	TREX1	Text_Mining(increases(reaction))	CTD
topotecan	TREX1	Text_Mining(affects(response to substance))	CTD
topotecan	TRIM2	Text_Mining(affects(response to substance))	CTD
topotecan	TRPC1	Text_Mining(affects(response to substance))	CTD
topotecan	TSPAN13	Text_Mining(affects(response to substance))	CTD
topotecan	TSPAN8	Text_Mining(affects(response to substance))	CTD
topotecan	TST	Text_Mining(affects(response to substance))	CTD
topotecan	TUBB6	Text_Mining(affects(response to substance))	CTD
topotecan	TUBGCP3	Text_Mining(affects(response to substance))	CTD
topotecan	TXNIP	Text_Mining(affects(response to substance))	CTD
topotecan	UBA1	Text_Mining(affects(response to substance))	CTD
topotecan	UBE2I	Text_Mining(affects(response to substance))	CTD
topotecan	UCHL1	Text_Mining(affects(response to substance))	CTD
topotecan	ULK2	Text_Mining(affects(response to substance))	CTD
topotecan	UNG	Text_Mining(affects(response to substance))	CTD
topotecan	URI1	Text_Mining(affects(response to substance))	CTD
topotecan	VCAN	Text_Mining(affects(response to substance))	CTD
topotecan	VEGFA	Text_Mining(affects(binding))	CTD
topotecan	VEGFA	Text_Mining(decreases(reaction))	CTD
topotecan	VEGFA	Text_Mining(increases(reaction))	CTD
topotecan	VEGFA	Text_Mining(increases(expression))	CTD
topotecan	VEGFA	Text_Mining(decreases(expression))	CTD
topotecan	VIM	Text_Mining(affects(response to substance))	CTD
topotecan	WEE1	Text_Mining(affects(response to substance))	CTD
topotecan	XIAP	Text_Mining(affects(cotreatment))	CTD
topotecan	XIAP	Text_Mining(decreases(reaction))	CTD
topotecan	XIAP	Text_Mining(increases(degradation))	CTD
topotecan	XIST	Text_Mining(affects(response to substance))	CTD
topotecan	ZBED5	Text_Mining(affects(response to substance))	CTD
topotecan	ZEB1	Text_Mining(affects(response to substance))	CTD
topotecan	ZNF710	Text_Mining(affects(response to substance))	CTD
topotecan	AKT1	Inhibition=None(Unspecified)	D4 ChEMBL
topotecan	TOP1	Inhibition=None(Unspecified)	D4 ChEMBL
topotecan	TOP1	Activity=None(Unspecified)	D4 ChEMBL