Drug Gene Type Source DL-Thyroxine CDKN1A Text_Mining(decreases(reaction)) CTD DL-Thyroxine CDKN1A Text_Mining(increases(expression)) CTD DL-Thyroxine CYP2C8 Text_Mining(decreases(activity)) CTD DL-Thyroxine DIO1 Text_Mining(affects(abundance)) CTD DL-Thyroxine DIO1 Text_Mining(increases(metabolic processing)) CTD DL-Thyroxine DIO1 Text_Mining(increases(abundance)) CTD DL-Thyroxine DIO1 Text_Mining(decreases(reaction)) CTD DL-Thyroxine DIO2 Text_Mining(decreases(activity)) CTD DL-Thyroxine DIO2 Text_Mining(decreases(reaction)) CTD DL-Thyroxine DIO2 Text_Mining(affects(metabolic processing)) CTD DL-Thyroxine DIO2 Text_Mining(increases(metabolic processing)) CTD DL-Thyroxine DIO2 Text_Mining(decreases(expression)) CTD DL-Thyroxine FOS Text_Mining(decreases(reaction)) CTD DL-Thyroxine FOS Text_Mining(increases(expression)) CTD DL-Thyroxine GH1 Text_Mining(decreases(abundance)) CTD DL-Thyroxine ITGB3 Text_Mining(affects(binding)) CTD DL-Thyroxine ITGB3 Text_Mining(decreases(activity)) CTD DL-Thyroxine ITGB3 Text_Mining(decreases(reaction)) CTD DL-Thyroxine JUN Text_Mining(decreases(reaction)) CTD DL-Thyroxine JUN Text_Mining(increases(expression)) CTD DL-Thyroxine MAPK1 Text_Mining(decreases(reaction)) CTD DL-Thyroxine MAPK1 Text_Mining(increases(activity)) CTD DL-Thyroxine MAPK1 Text_Mining(increases(phosphorylation)) CTD DL-Thyroxine MAPK3 Text_Mining(decreases(reaction)) CTD DL-Thyroxine MAPK3 Text_Mining(increases(activity)) CTD DL-Thyroxine MAPK3 Text_Mining(increases(phosphorylation)) CTD DL-Thyroxine NCOR1 Text_Mining(affects(binding)) CTD DL-Thyroxine NCOR1 Text_Mining(decreases(reaction)) CTD DL-Thyroxine NCOR1 Text_Mining(decreases(activity)) CTD DL-Thyroxine NCOR2 Text_Mining(affects(binding)) CTD DL-Thyroxine NCOR2 Text_Mining(decreases(reaction)) CTD DL-Thyroxine NCOR2 Text_Mining(decreases(activity)) CTD DL-Thyroxine PCNA Text_Mining(decreases(reaction)) CTD DL-Thyroxine PCNA Text_Mining(increases(expression)) CTD DL-Thyroxine PTGS2 Text_Mining(affects(localization)) CTD DL-Thyroxine PTGS2 Text_Mining(decreases(reaction)) CTD DL-Thyroxine SERPINA7 Text_Mining(affects(binding)) CTD DL-Thyroxine SERPINA7 Text_Mining(decreases(reaction)) CTD DL-Thyroxine SIRT1 Text_Mining(increases(expression)) CTD DL-Thyroxine SRC Text_Mining(affects(binding)) CTD DL-Thyroxine SRC Text_Mining(decreases(activity)) CTD DL-Thyroxine SRC Text_Mining(decreases(reaction)) CTD DL-Thyroxine SULT1A1 Text_Mining(affects(sulfation)) CTD DL-Thyroxine SULT1A1 Text_Mining(increases(sulfation)) CTD DL-Thyroxine SULT1A1 Text_Mining(decreases(reaction)) CTD DL-Thyroxine SULT1A3 Text_Mining(decreases(reaction)) CTD DL-Thyroxine SULT1A3 Text_Mining(increases(sulfation)) CTD DL-Thyroxine SULT4A1 Text_Mining(increases(metabolic processing)) CTD DL-Thyroxine THRA Text_Mining(affects(binding)) CTD DL-Thyroxine THRB Text_Mining(affects(binding)) CTD DL-Thyroxine THRB Text_Mining(decreases(reaction)) CTD DL-Thyroxine THRB Text_Mining(decreases(activity)) CTD DL-Thyroxine THRB Text_Mining(increases(activity)) CTD DL-Thyroxine TP53 Text_Mining(decreases(reaction)) CTD DL-Thyroxine TP53 Text_Mining(increases(activity)) CTD DL-Thyroxine TTR Text_Mining(affects(binding)) CTD DL-Thyroxine TTR Text_Mining(decreases(reaction)) CTD DL-Thyroxine ALDH1A1 Potency=15.8489(uM) D4 PubChem DL-Thyroxine ALDH1A1 Potency=15848.9(nM) D4 ChEMBL DL-Thyroxine ALOX15 Potency=12.5893(uM) D4 PubChem DL-Thyroxine ALOX15 Potency=12589.3(nM) D4 ChEMBL DL-Thyroxine HSD17B10 Potency=10000.0(nM) D4 ChEMBL