Drug Gene Type Source pyrilamine BCHE Text_Mining(decreases(activity)) CTD pyrilamine CXCL8 Text_Mining(decreases(response to substance)) CTD pyrilamine CXCL8 Text_Mining(increases(reaction)) CTD pyrilamine F3 Text_Mining(decreases(reaction)) CTD pyrilamine F3 Text_Mining(increases(activity)) CTD pyrilamine F3 Text_Mining(increases(expression)) CTD pyrilamine HRH1 Text_Mining(affects(binding)) CTD pyrilamine HRH1 Text_Mining(decreases(reaction)) CTD pyrilamine HRH1 Text_Mining(affects(reaction)) CTD pyrilamine HRH1 Text_Mining(decreases(response to substance)) CTD pyrilamine HRH1 Text_Mining(increases(reaction)) CTD pyrilamine HRH1 Text_Mining(decreases(activity)) CTD pyrilamine KCNH2 Text_Mining(affects(activity)) CTD pyrilamine KCNH2 Text_Mining(decreases(reaction)) CTD pyrilamine KCNH2 Text_Mining(increases(transport)) CTD pyrilamine KNG1 Text_Mining(decreases(activity)) CTD pyrilamine MAPK1 Text_Mining(decreases(reaction)) CTD pyrilamine MAPK1 Text_Mining(increases(activity)) CTD pyrilamine MAPK1 Text_Mining(increases(phosphorylation)) CTD pyrilamine MAPK3 Text_Mining(decreases(reaction)) CTD pyrilamine MAPK3 Text_Mining(increases(activity)) CTD pyrilamine MAPK3 Text_Mining(increases(phosphorylation)) CTD pyrilamine SLC22A2 Text_Mining(decreases(reaction)) CTD pyrilamine SLC22A2 Text_Mining(increases(uptake)) CTD pyrilamine SLC6A3 Text_Mining(affects(activity)) CTD pyrilamine SLC6A3 Text_Mining(affects(binding)) CTD pyrilamine SLC6A4 Text_Mining(affects(binding)) CTD pyrilamine AR AR Potency (uM)=70.8978(uM) D4 PubChem pyrilamine CYP1A2 Inhibition=None(Unspecified) D4 ChEMBL pyrilamine CYP2C19 Inhibition=None(Unspecified) D4 ChEMBL pyrilamine CYP2C9 Inhibition=None(Unspecified) D4 ChEMBL pyrilamine CYP2D6 Potency=0.1(uM) D4 PubChem pyrilamine CYP2D6 Potency=0.1259(uM) D4 PubChem pyrilamine CYP2D6 Potency=0.5012(uM) D4 PubChem pyrilamine CYP2D6 None=None(uM) D4 PubChem pyrilamine CYP2D6 Potency=100.0(nM) D4 ChEMBL pyrilamine CYP2D6 AC50=100.0(nM) D4 ChEMBL pyrilamine CYP2D6 AC50=125.89(nM) D4 ChEMBL pyrilamine CYP2D6 Potency=501.2(nM) D4 ChEMBL pyrilamine CYP2D6 Potency=125.9(nM) D4 ChEMBL pyrilamine CYP2D6 AC50=501.19(nM) D4 ChEMBL pyrilamine CYP3A4 Inhibition=None(Unspecified) D4 ChEMBL pyrilamine HRH1 Activity=None(Unspecified) D4 ChEMBL pyrilamine KCNH2 Potency=12.5893(uM) D4 PubChem