Drug Gene Type Source nortriptyline ABCB1 Text_Mining(affects(response to substance)) CTD nortriptyline CASP3 Text_Mining(increases(activity)) CTD nortriptyline CASP3 Text_Mining(increases(reaction)) CTD nortriptyline CASP7 Text_Mining(increases(activity)) CTD nortriptyline CASP7 Text_Mining(increases(reaction)) CTD nortriptyline CYP1A2 Text_Mining(increases(metabolic processing)) CTD nortriptyline CYP2C8 Text_Mining(decreases(activity)) CTD nortriptyline CYP2C8 Text_Mining(decreases(reaction)) CTD nortriptyline CYP2D6 Text_Mining(decreases(response to substance)) CTD nortriptyline CYP2D6 Text_Mining(increases(hydroxylation)) CTD nortriptyline CYP2D6 Text_Mining(increases(metabolic processing)) CTD nortriptyline CYP2D6 Text_Mining(decreases(reaction)) CTD nortriptyline CYP3A4 Text_Mining(increases(metabolic processing)) CTD nortriptyline CYP3A5 Text_Mining(increases(metabolic processing)) CTD nortriptyline GNB3 Text_Mining(decreases(response to substance)) CTD nortriptyline GNB3 Text_Mining(increases(response to substance)) CTD nortriptyline HTR2C Text_Mining(decreases(expression)) CTD nortriptyline IL1A Text_Mining(affects(cotreatment)) CTD nortriptyline IL1A Text_Mining(increases(response to substance)) CTD nortriptyline IL6 Text_Mining(affects(cotreatment)) CTD nortriptyline IL6 Text_Mining(increases(response to substance)) CTD nortriptyline KCNH2 Text_Mining(decreases(reaction)) CTD nortriptyline KCNH2 Text_Mining(increases(transport)) CTD nortriptyline PF4 Text_Mining(affects(expression)) CTD nortriptyline PPBP Text_Mining(affects(expression)) CTD nortriptyline SLC22A2 Text_Mining(decreases(reaction)) CTD nortriptyline SLC22A2 Text_Mining(increases(uptake)) CTD nortriptyline SLC6A2 Text_Mining(affects(response to substance)) CTD nortriptyline SLC6A4 Text_Mining(decreases(response to substance)) CTD nortriptyline SLC6A4 Text_Mining(affects(response to substance)) CTD nortriptyline SLC6A4 Text_Mining(increases(response to substance)) CTD nortriptyline TNF Text_Mining(affects(cotreatment)) CTD nortriptyline TNF Text_Mining(increases(response to substance)) CTD nortriptyline ATXN2 Potency=15.8489(uM) D4 PubChem nortriptyline ATXN2 Potency=17.7828(uM) D4 PubChem nortriptyline CYP1A2 None=None(uM) D4 PubChem nortriptyline CYP2D6 Potency=3.1623(uM) D4 PubChem nortriptyline CYP2D6 Potency=6.3096(uM) D4 PubChem nortriptyline CYP2D6 Potency=15.8489(uM) D4 PubChem nortriptyline CYP2D6 None=None(uM) D4 PubChem nortriptyline CYP2D6 AC50=15848.9(nM) D4 ChEMBL nortriptyline CYP2D6 AC50=6309.57(nM) D4 ChEMBL nortriptyline CYP2D6 Potency=15848.9(nM) D4 ChEMBL nortriptyline CYP2D6 Potency=3162.3(nM) D4 ChEMBL nortriptyline CYP2D6 Potency=6309.6(nM) D4 ChEMBL nortriptyline DRD1 Potency=19.9526(uM) D4 PubChem nortriptyline DRD1 Potency=19952.6(nM) D4 ChEMBL nortriptyline TDP1 Potency=20.5962(uM) D4 PubChem nortriptyline TP53 Potency=19.9526(uM) D4 PubChem nortriptyline TP53 Potency=19952.6(nM) D4 ChEMBL