Drug Gene Type Source histamine ABL1 Text_Mining(affects(binding)) CTD histamine ABL1 Text_Mining(decreases(reaction)) CTD histamine ABL1 Text_Mining(increases(chemical synthesis)) CTD histamine ADRB2 Text_Mining(increases(activity)) CTD histamine ADRB2 Text_Mining(increases(reaction)) CTD histamine ALOX5 Text_Mining(increases(abundance)) CTD histamine ALOX5 Text_Mining(increases(response to substance)) CTD histamine ALOX5 Text_Mining(decreases(reaction)) CTD histamine ALOX5AP Text_Mining(increases(abundance)) CTD histamine ALOX5AP Text_Mining(increases(response to substance)) CTD histamine ALOX5AP Text_Mining(decreases(reaction)) CTD histamine AOC1 Text_Mining(increases(metabolic processing)) CTD histamine AQP5 Text_Mining(affects(localization)) CTD histamine BCR Text_Mining(affects(binding)) CTD histamine BCR Text_Mining(decreases(reaction)) CTD histamine BCR Text_Mining(increases(chemical synthesis)) CTD histamine CCL2 Text_Mining(increases(expression)) CTD histamine CCL2 Text_Mining(increases(reaction)) CTD histamine CCND1 Text_Mining(decreases(expression)) CTD histamine CCND1 Text_Mining(increases(response to substance)) CTD histamine CD14 Text_Mining(affects(expression)) CTD histamine CD14 Text_Mining(affects(reaction)) CTD histamine CD40 Text_Mining(decreases(chemical synthesis)) CTD histamine CD40 Text_Mining(decreases(expression)) CTD histamine CD40 Text_Mining(affects(binding)) CTD histamine CD40 Text_Mining(decreases(reaction)) CTD histamine CD40 Text_Mining(increases(activity)) CTD histamine CD80 Text_Mining(decreases(reaction)) CTD histamine CD80 Text_Mining(increases(expression)) CTD histamine CDK2 Text_Mining(decreases(expression)) CTD histamine CDK2 Text_Mining(increases(response to substance)) CTD histamine CDKN1A Text_Mining(increases(expression)) CTD histamine CDKN1A Text_Mining(increases(response to substance)) CTD histamine CDKN1B Text_Mining(increases(expression)) CTD histamine CDKN1B Text_Mining(increases(response to substance)) CTD histamine CLCA1 Text_Mining(increases(expression)) CTD histamine CSF2 Text_Mining(increases(expression)) CTD histamine CSF2 Text_Mining(increases(secretion)) CTD histamine CSF2 Text_Mining(increases(reaction)) CTD histamine CXCL8 Text_Mining(decreases(reaction)) CTD histamine CXCL8 Text_Mining(increases(expression)) CTD histamine CXCL8 Text_Mining(affects(binding)) CTD histamine CXCL8 Text_Mining(increases(activity)) CTD histamine CXCL8 Text_Mining(increases(reaction)) CTD histamine EDN1 Text_Mining(affects(cotreatment)) CTD histamine EDN1 Text_Mining(decreases(activity)) CTD histamine EGFR Text_Mining(affects(reaction)) CTD histamine EGFR Text_Mining(increases(secretion)) CTD histamine F3 Text_Mining(decreases(reaction)) CTD histamine F3 Text_Mining(increases(expression)) CTD histamine F3 Text_Mining(increases(reaction)) CTD histamine F3 Text_Mining(affects(cotreatment)) CTD histamine F3 Text_Mining(increases(activity)) CTD histamine FCER1A Text_Mining(affects(secretion)) CTD histamine FOS Text_Mining(affects(binding)) CTD histamine FOS Text_Mining(decreases(reaction)) CTD histamine FOS Text_Mining(increases(activity)) CTD histamine FOS Text_Mining(increases(expression)) CTD histamine GUSB Text_Mining(affects(binding)) CTD histamine GUSB Text_Mining(decreases(reaction)) CTD histamine GUSB Text_Mining(increases(activity)) CTD histamine GUSB Text_Mining(increases(expression)) CTD histamine GUSB Text_Mining(increases(reaction)) CTD histamine HDC Text_Mining(decreases(expression)) CTD histamine HDC Text_Mining(decreases(secretion)) CTD histamine HNMT Text_Mining(increases(methylation)) CTD histamine HNMT Text_Mining(decreases(reaction)) CTD histamine HRH1 Text_Mining(decreases(abundance)) CTD histamine HRH1 Text_Mining(decreases(reaction)) CTD histamine HRH1 Text_Mining(increases(reaction)) CTD histamine HRH1 Text_Mining(affects(cotreatment)) CTD histamine HRH1 Text_Mining(decreases(activity)) CTD histamine HRH1 Text_Mining(affects(binding)) CTD histamine HRH1 Text_Mining(increases(abundance)) CTD histamine HRH1 Text_Mining(increases(activity)) CTD histamine HRH1 Text_Mining(increases(expression)) CTD histamine HRH1 Text_Mining(affects(reaction)) CTD histamine HRH1 Text_Mining(increases(export)) CTD histamine HRH1 Text_Mining(increases(metabolic processing)) CTD histamine HRH1 Text_Mining(decreases(expression)) CTD histamine HRH2 Text_Mining(affects(binding)) CTD histamine HRH2 Text_Mining(decreases(reaction)) CTD histamine HRH2 Text_Mining(increases(abundance)) CTD histamine HRH2 Text_Mining(increases(activity)) CTD histamine HRH2 Text_Mining(affects(cotreatment)) CTD histamine HRH2 Text_Mining(decreases(activity)) CTD histamine HRH2 Text_Mining(decreases(response to substance)) CTD histamine HRH2 Text_Mining(increases(expression)) CTD histamine HRH2 Text_Mining(increases(reaction)) CTD histamine HRH2 Text_Mining(decreases(expression)) CTD histamine HRH2 Text_Mining(affects(expression)) CTD histamine HRH2 Text_Mining(affects(localization)) CTD histamine HRH2 Text_Mining(affects(degradation)) CTD histamine HRH2 Text_Mining(affects(reaction)) CTD histamine HRH3 Text_Mining(affects(binding)) CTD histamine HRH3 Text_Mining(increases(activity)) CTD histamine HRH4 Text_Mining(decreases(reaction)) CTD histamine HRH4 Text_Mining(increases(response to substance)) CTD histamine HRH4 Text_Mining(affects(binding)) CTD histamine HRH4 Text_Mining(increases(activity)) CTD histamine HRH4 Text_Mining(increases(abundance)) CTD histamine HRH4 Text_Mining(increases(phosphorylation)) CTD histamine HRH4 Text_Mining(increases(reaction)) CTD histamine HRH4 Text_Mining(decreases(expression)) CTD histamine HRH4 Text_Mining(increases(expression)) CTD histamine ICAM1 Text_Mining(decreases(reaction)) CTD histamine ICAM1 Text_Mining(increases(expression)) CTD histamine ICAM1 Text_Mining(affects(reaction)) CTD histamine IFNG Text_Mining(decreases(reaction)) CTD histamine IFNG Text_Mining(increases(expression)) CTD histamine IFNG Text_Mining(affects(expression)) CTD histamine IFNG Text_Mining(affects(binding)) CTD histamine IFNG Text_Mining(decreases(expression)) CTD histamine IFNG Text_Mining(increases(activity)) CTD histamine IFNG Text_Mining(affects(reaction)) CTD histamine IFNG Text_Mining(increases(reaction)) CTD histamine IL10 Text_Mining(decreases(expression)) CTD histamine IL10 Text_Mining(decreases(reaction)) CTD histamine IL10 Text_Mining(affects(reaction)) CTD histamine IL10 Text_Mining(affects(binding)) CTD histamine IL10 Text_Mining(increases(expression)) CTD histamine IL12A Text_Mining(decreases(expression)) CTD histamine IL12A Text_Mining(increases(activity)) CTD histamine IL12A Text_Mining(increases(reaction)) CTD histamine IL12A Text_Mining(affects(binding)) CTD histamine IL12A Text_Mining(decreases(reaction)) CTD histamine IL12A Text_Mining(increases(expression)) CTD histamine IL12A Text_Mining(affects(reaction)) CTD histamine IL12B Text_Mining(decreases(expression)) CTD histamine IL12B Text_Mining(increases(activity)) CTD histamine IL12B Text_Mining(increases(reaction)) CTD histamine IL12B Text_Mining(affects(binding)) CTD histamine IL12B Text_Mining(decreases(reaction)) CTD histamine IL12B Text_Mining(increases(expression)) CTD histamine IL12B Text_Mining(affects(reaction)) CTD histamine IL16 Text_Mining(decreases(reaction)) CTD histamine IL16 Text_Mining(increases(expression)) CTD histamine IL16 Text_Mining(increases(reaction)) CTD histamine IL18 Text_Mining(decreases(expression)) CTD histamine IL18 Text_Mining(decreases(reaction)) CTD histamine IL18 Text_Mining(increases(expression)) CTD histamine IL18 Text_Mining(affects(binding)) CTD histamine IL18 Text_Mining(affects(reaction)) CTD histamine IL5 Text_Mining(decreases(reaction)) CTD histamine IL5 Text_Mining(increases(expression)) CTD histamine IL6 Text_Mining(decreases(reaction)) CTD histamine IL6 Text_Mining(increases(expression)) CTD histamine IL6 Text_Mining(increases(reaction)) CTD histamine CXCL8 Text_Mining(increases(secretion)) CTD histamine KCNQ2 Text_Mining(affects(cotreatment)) CTD histamine KCNQ2 Text_Mining(decreases(activity)) CTD histamine KCNQ2 Text_Mining(decreases(reaction)) CTD histamine KCNQ3 Text_Mining(affects(cotreatment)) CTD histamine KCNQ3 Text_Mining(decreases(activity)) CTD histamine KCNQ3 Text_Mining(decreases(reaction)) CTD histamine LTC4S Text_Mining(decreases(response to substance)) CTD histamine MAPK1 Text_Mining(decreases(reaction)) CTD histamine MAPK1 Text_Mining(increases(phosphorylation)) CTD histamine MAPK1 Text_Mining(affects(binding)) CTD histamine MAPK1 Text_Mining(increases(activity)) CTD histamine MAPK1 Text_Mining(increases(reaction)) CTD histamine MAPK3 Text_Mining(decreases(reaction)) CTD histamine MAPK3 Text_Mining(increases(phosphorylation)) CTD histamine MAPK3 Text_Mining(affects(binding)) CTD histamine MAPK3 Text_Mining(increases(activity)) CTD histamine MAPK3 Text_Mining(increases(reaction)) CTD histamine MMP1 Text_Mining(decreases(reaction)) CTD histamine MMP1 Text_Mining(increases(expression)) CTD histamine MMP1 Text_Mining(increases(secretion)) CTD histamine MMP1 Text_Mining(affects(reaction)) CTD histamine MUC5AC Text_Mining(decreases(reaction)) CTD histamine MUC5AC Text_Mining(increases(expression)) CTD histamine NFKB1 Text_Mining(affects(localization)) CTD histamine NFKB1 Text_Mining(increases(reaction)) CTD histamine NOS2 Text_Mining(decreases(reaction)) CTD histamine NOS2 Text_Mining(increases(phosphorylation)) CTD histamine NOS2 Text_Mining(increases(reaction)) CTD histamine NOS2 Text_Mining(affects(cotreatment)) CTD histamine NOS2 Text_Mining(affects(reaction)) CTD histamine PDE4B Text_Mining(decreases(reaction)) CTD histamine PDE4B Text_Mining(increases(expression)) CTD histamine PLA2G4A Text_Mining(decreases(reaction)) CTD histamine PLA2G4A Text_Mining(increases(expression)) CTD histamine PRKAA1 Text_Mining(affects(cotreatment)) CTD histamine PRKAA1 Text_Mining(affects(reaction)) CTD histamine PRKAA1 Text_Mining(increases(phosphorylation)) CTD histamine PRKAA2 Text_Mining(affects(cotreatment)) CTD histamine PRKAA2 Text_Mining(affects(reaction)) CTD histamine PRKAA2 Text_Mining(increases(phosphorylation)) CTD histamine PTGS2 Text_Mining(increases(expression)) CTD histamine PTGS2 Text_Mining(increases(reaction)) CTD histamine PTGS2 Text_Mining(increases(chemical synthesis)) CTD histamine PTGS2 Text_Mining(affects(reaction)) CTD histamine PTPRC Text_Mining(decreases(chemical synthesis)) CTD histamine PTPRC Text_Mining(decreases(expression)) CTD histamine PTPRC Text_Mining(affects(binding)) CTD histamine PTPRC Text_Mining(decreases(reaction)) CTD histamine PTPRC Text_Mining(increases(activity)) CTD histamine RELA Text_Mining(affects(localization)) CTD histamine RELA Text_Mining(increases(reaction)) CTD histamine RELA Text_Mining(affects(binding)) CTD histamine RELA Text_Mining(increases(activity)) CTD histamine SLC18A1 Text_Mining(decreases(reaction)) CTD histamine SLC18A1 Text_Mining(increases(uptake)) CTD histamine SLC18A2 Text_Mining(affects(binding)) CTD histamine SLC22A3 Text_Mining(decreases(reaction)) CTD histamine SLC22A3 Text_Mining(increases(uptake)) CTD histamine SLC22A3 Text_Mining(affects(uptake)) CTD histamine STK11 Text_Mining(increases(phosphorylation)) CTD histamine STK11 Text_Mining(increases(abundance)) CTD histamine STK11 Text_Mining(increases(reaction)) CTD histamine TAC1 Text_Mining(decreases(reaction)) CTD histamine TAC1 Text_Mining(increases(secretion)) CTD histamine TLR2 Text_Mining(increases(expression)) CTD histamine TLR2 Text_Mining(increases(reaction)) CTD histamine TLR2 Text_Mining(increases(chemical synthesis)) CTD histamine TLR2 Text_Mining(affects(reaction)) CTD histamine TNF Text_Mining(decreases(reaction)) CTD histamine TNF Text_Mining(increases(expression)) CTD histamine TNF Text_Mining(affects(localization)) CTD histamine TNF Text_Mining(increases(reaction)) CTD histamine TNF Text_Mining(affects(reaction)) CTD histamine UCP2 Text_Mining(decreases(secretion)) CTD histamine ARNT AC50_uM=23.08(uM) D4 PubChem histamine ARNT None=None(uM) D4 PubChem histamine EHMT2 Potency=8.4368(uM) D4 PubChem histamine LMNA Potency=0.8913(uM) D4 PubChem histamine TACC3 AC50_uM=23.08(uM) D4 PubChem histamine TACC3 None=None(uM) D4 PubChem histamine USP1 Potency=44.6684(uM) D4 PubChem