Drug Gene Type Source diphenhydramine BCHE Text_Mining(decreases(activity)) CTD diphenhydramine BCHE Text_Mining(affects(reaction)) CTD diphenhydramine CXCL8 Text_Mining(decreases(reaction)) CTD diphenhydramine CXCL8 Text_Mining(increases(expression)) CTD diphenhydramine CXCL8 Text_Mining(decreases(response to substance)) CTD diphenhydramine CXCL8 Text_Mining(increases(reaction)) CTD diphenhydramine F3 Text_Mining(decreases(reaction)) CTD diphenhydramine F3 Text_Mining(increases(expression)) CTD diphenhydramine HRH1 Text_Mining(affects(binding)) CTD diphenhydramine HRH1 Text_Mining(decreases(activity)) CTD diphenhydramine HRH1 Text_Mining(increases(activity)) CTD diphenhydramine HRH1 Text_Mining(decreases(reaction)) CTD diphenhydramine HRH1 Text_Mining(decreases(response to substance)) CTD diphenhydramine HRH1 Text_Mining(increases(reaction)) CTD diphenhydramine IL6 Text_Mining(decreases(reaction)) CTD diphenhydramine IL6 Text_Mining(increases(expression)) CTD diphenhydramine MAPK8 Text_Mining(increases(activity)) CTD diphenhydramine NR1I3 Text_Mining(affects(binding)) CTD diphenhydramine NR1I3 Text_Mining(affects(cotreatment)) CTD diphenhydramine NR1I3 Text_Mining(increases(activity)) CTD diphenhydramine PLA2G4A Text_Mining(decreases(reaction)) CTD diphenhydramine PLA2G4A Text_Mining(increases(expression)) CTD diphenhydramine SLC22A1 Text_Mining(decreases(reaction)) CTD diphenhydramine SLC22A1 Text_Mining(increases(transport)) CTD diphenhydramine SLC22A2 Text_Mining(decreases(reaction)) CTD diphenhydramine SLC22A2 Text_Mining(increases(transport)) CTD diphenhydramine SLC22A2 Text_Mining(increases(uptake)) CTD diphenhydramine SLC22A3 Text_Mining(decreases(reaction)) CTD diphenhydramine SLC22A3 Text_Mining(increases(transport)) CTD diphenhydramine CHRM5 None=None(uM) D4 PubChem diphenhydramine CYP1A2 None=None(uM) D4 PubChem diphenhydramine CYP1A2 Inhibition=None(Unspecified) D4 ChEMBL diphenhydramine CYP2C19 Inhibition=None(Unspecified) D4 ChEMBL diphenhydramine CYP2C9 Inhibition=None(Unspecified) D4 ChEMBL diphenhydramine CYP2D6 Potency=3.9811(uM) D4 PubChem diphenhydramine CYP2D6 Potency=12.5893(uM) D4 PubChem diphenhydramine CYP2D6 None=None(uM) D4 PubChem diphenhydramine CYP2D6 Potency=3981.1(nM) D4 ChEMBL diphenhydramine CYP2D6 AC50=12589.2(nM) D4 ChEMBL diphenhydramine CYP2D6 AC50=3981.07(nM) D4 ChEMBL diphenhydramine CYP2D6 Inhibition=None(Unspecified) D4 ChEMBL diphenhydramine CYP2D6 Potency=12589.3(nM) D4 ChEMBL diphenhydramine CYP3A4 Inhibition=None(Unspecified) D4 ChEMBL diphenhydramine DRD3 None=None(uM) D4 PubChem