Drug	Gene	Type	Source
caffeine	ACAT2	Text_Mining(decreases(expression))	CTD
caffeine	ACIN1	Text_Mining(increases(expression))	CTD
caffeine	ACSL3	Text_Mining(increases(expression))	CTD
caffeine	ADORA1	Text_Mining(decreases(activity))	CTD
caffeine	ADORA2A	Text_Mining(affects(response to substance))	CTD
caffeine	ADORA2A	Text_Mining(increases(response to substance))	CTD
caffeine	ADORA2A	Text_Mining(decreases(activity))	CTD
caffeine	ADORA2B	Text_Mining(decreases(activity))	CTD
caffeine	ADORA2B	Text_Mining(decreases(expression))	CTD
caffeine	ADORA2B	Text_Mining(decreases(reaction))	CTD
caffeine	AKT1	Text_Mining(decreases(reaction))	CTD
caffeine	AKT1	Text_Mining(increases(phosphorylation))	CTD
caffeine	AKT1	Text_Mining(decreases(response to substance))	CTD
caffeine	AKT1	Text_Mining(decreases(expression))	CTD
caffeine	AKT1	Text_Mining(decreases(phosphorylation))	CTD
caffeine	ALDH18A1	Text_Mining(decreases(expression))	CTD
caffeine	ANG	Text_Mining(decreases(expression))	CTD
caffeine	APOA1	Text_Mining(affects(cotreatment))	CTD
caffeine	APOA1	Text_Mining(increases(expression))	CTD
caffeine	APOA2	Text_Mining(affects(cotreatment))	CTD
caffeine	APOA2	Text_Mining(decreases(expression))	CTD
caffeine	APOB	Text_Mining(affects(cotreatment))	CTD
caffeine	APOB	Text_Mining(decreases(expression))	CTD
caffeine	APOC1	Text_Mining(affects(cotreatment))	CTD
caffeine	APOC1	Text_Mining(increases(expression))	CTD
caffeine	APOC2	Text_Mining(affects(cotreatment))	CTD
caffeine	APOC2	Text_Mining(decreases(expression))	CTD
caffeine	APOC3	Text_Mining(affects(cotreatment))	CTD
caffeine	APOC3	Text_Mining(decreases(expression))	CTD
caffeine	ARL6IP1	Text_Mining(increases(expression))	CTD
caffeine	ASNS	Text_Mining(decreases(expression))	CTD
caffeine	ATM	Text_Mining(decreases(reaction))	CTD
caffeine	ATM	Text_Mining(increases(phosphorylation))	CTD
caffeine	ATM	Text_Mining(increases(activity))	CTD
caffeine	ATM	Text_Mining(decreases(activity))	CTD
caffeine	ATM	Text_Mining(affects(cotreatment))	CTD
caffeine	ATM	Text_Mining(decreases(response to substance))	CTD
caffeine	ATP5J2	Text_Mining(decreases(expression))	CTD
caffeine	ATR	Text_Mining(affects(activity))	CTD
caffeine	ATR	Text_Mining(decreases(reaction))	CTD
caffeine	ATR	Text_Mining(increases(activity))	CTD
caffeine	ATR	Text_Mining(increases(phosphorylation))	CTD
caffeine	ATR	Text_Mining(increases(reaction))	CTD
caffeine	ATR	Text_Mining(affects(cotreatment))	CTD
caffeine	ATR	Text_Mining(decreases(activity))	CTD
caffeine	ATR	Text_Mining(decreases(response to substance))	CTD
caffeine	BAX	Text_Mining(increases(expression))	CTD
caffeine	BBC3	Text_Mining(decreases(reaction))	CTD
caffeine	BBC3	Text_Mining(increases(expression))	CTD
caffeine	BID	Text_Mining(decreases(reaction))	CTD
caffeine	BID	Text_Mining(increases(cleavage))	CTD
caffeine	BUB1	Text_Mining(affects(cotreatment))	CTD
caffeine	BUB1	Text_Mining(increases(expression))	CTD
caffeine	CALU	Text_Mining(decreases(expression))	CTD
caffeine	CAPN1	Text_Mining(affects(cotreatment))	CTD
caffeine	CAPN1	Text_Mining(increases(activity))	CTD
caffeine	CAPN1	Text_Mining(increases(reaction))	CTD
caffeine	CASP2	Text_Mining(decreases(reaction))	CTD
caffeine	CASP2	Text_Mining(increases(activity))	CTD
caffeine	CASP2	Text_Mining(increases(cleavage))	CTD
caffeine	CASP3	Text_Mining(affects(cleavage))	CTD
caffeine	CASP3	Text_Mining(affects(cotreatment))	CTD
caffeine	CASP3	Text_Mining(increases(cleavage))	CTD
caffeine	CASP3	Text_Mining(decreases(reaction))	CTD
caffeine	CASP3	Text_Mining(increases(activity))	CTD
caffeine	CASP3	Text_Mining(increases(expression))	CTD
caffeine	CASP9	Text_Mining(decreases(reaction))	CTD
caffeine	CASP9	Text_Mining(increases(activity))	CTD
caffeine	CASP9	Text_Mining(increases(cleavage))	CTD
caffeine	CASP9	Text_Mining(increases(expression))	CTD
caffeine	CCNB1	Text_Mining(decreases(reaction))	CTD
caffeine	CCNB1	Text_Mining(increases(expression))	CTD
caffeine	CDC25C	Text_Mining(affects(binding))	CTD
caffeine	CDC25C	Text_Mining(decreases(reaction))	CTD
caffeine	CDC25C	Text_Mining(increases(phosphorylation))	CTD
caffeine	CDC25C	Text_Mining(decreases(expression))	CTD
caffeine	CDK1	Text_Mining(decreases(reaction))	CTD
caffeine	CDK1	Text_Mining(increases(phosphorylation))	CTD
caffeine	CDK1	Text_Mining(decreases(phosphorylation))	CTD
caffeine	CDK1	Text_Mining(increases(activity))	CTD
caffeine	CDK2	Text_Mining(decreases(activity))	CTD
caffeine	CDK4	Text_Mining(decreases(expression))	CTD
caffeine	CDKN1A	Text_Mining(decreases(reaction))	CTD
caffeine	CDKN1A	Text_Mining(increases(expression))	CTD
caffeine	CHEK1	Text_Mining(decreases(reaction))	CTD
caffeine	CHEK1	Text_Mining(increases(activity))	CTD
caffeine	CHEK1	Text_Mining(increases(phosphorylation))	CTD
caffeine	CHEK1	Text_Mining(increases(reaction))	CTD
caffeine	CHEK1	Text_Mining(affects(cotreatment))	CTD
caffeine	CHEK1	Text_Mining(decreases(phosphorylation))	CTD
caffeine	CHEK2	Text_Mining(decreases(reaction))	CTD
caffeine	CHEK2	Text_Mining(increases(phosphorylation))	CTD
caffeine	CHEK2	Text_Mining(affects(cotreatment))	CTD
caffeine	CHEK2	Text_Mining(increases(activity))	CTD
caffeine	CHEK2	Text_Mining(increases(reaction))	CTD
caffeine	CHEK2	Text_Mining(decreases(activity))	CTD
caffeine	CTSB	Text_Mining(affects(cotreatment))	CTD
caffeine	CTSB	Text_Mining(increases(secretion))	CTD
caffeine	CYC1	Text_Mining(decreases(expression))	CTD
caffeine	CYCS	Text_Mining(affects(localization))	CTD
caffeine	CYCS	Text_Mining(decreases(reaction))	CTD
caffeine	CYP1A2	Text_Mining(decreases(activity))	CTD
caffeine	CYP1A2	Text_Mining(decreases(methylation))	CTD
caffeine	CYP1A2	Text_Mining(decreases(reaction))	CTD
caffeine	CYP1A2	Text_Mining(affects(metabolic processing))	CTD
caffeine	CYP1A2	Text_Mining(affects(binding))	CTD
caffeine	CYP1A2	Text_Mining(increases(metabolic processing))	CTD
caffeine	CYP1A2	Text_Mining(increases(reaction))	CTD
caffeine	CYP2A6	Text_Mining(affects(metabolic processing))	CTD
caffeine	CYP2A6	Text_Mining(increases(activity))	CTD
caffeine	CYP2A6	Text_Mining(increases(metabolic processing))	CTD
caffeine	CYP2D6	Text_Mining(affects(metabolic processing))	CTD
caffeine	CYP2E1	Text_Mining(affects(metabolic processing))	CTD
caffeine	CYP3A4	Text_Mining(decreases(activity))	CTD
caffeine	CYP4B1	Text_Mining(increases(expression))	CTD
caffeine	DAD1	Text_Mining(decreases(expression))	CTD
caffeine	DCT	Text_Mining(increases(expression))	CTD
caffeine	DRD2	Text_Mining(affects(response to substance))	CTD
caffeine	EIF1	Text_Mining(increases(expression))	CTD
caffeine	EIF4EBP1	Text_Mining(decreases(expression))	CTD
caffeine	EIF4EBP1	Text_Mining(increases(expression))	CTD
caffeine	GH1	Text_Mining(increases(metabolic processing))	CTD
caffeine	GH1	Text_Mining(increases(reaction))	CTD
caffeine	GLRX	Text_Mining(decreases(expression))	CTD
caffeine	GLT8D1	Text_Mining(decreases(expression))	CTD
caffeine	GLUD1	Text_Mining(decreases(expression))	CTD
caffeine	GSK3B	Text_Mining(increases(phosphorylation))	CTD
caffeine	GSK3B	Text_Mining(decreases(reaction))	CTD
caffeine	GSTO1	Text_Mining(decreases(expression))	CTD
caffeine	H2AFX	Text_Mining(decreases(reaction))	CTD
caffeine	H2AFX	Text_Mining(increases(phosphorylation))	CTD
caffeine	H2AFX	Text_Mining(increases(reaction))	CTD
caffeine	HSD11B2	Text_Mining(decreases(activity))	CTD
caffeine	HSD11B2	Text_Mining(decreases(expression))	CTD
caffeine	HSD11B2	Text_Mining(decreases(reaction))	CTD
caffeine	IGFBP1	Text_Mining(increases(expression))	CTD
caffeine	INS	Text_Mining(decreases(reaction))	CTD
caffeine	INS	Text_Mining(increases(phosphorylation))	CTD
caffeine	ITPR1	Text_Mining(decreases(expression))	CTD
caffeine	LDHA	Text_Mining(decreases(expression))	CTD
caffeine	MAPK1	Text_Mining(increases(expression))	CTD
caffeine	MAPK3	Text_Mining(increases(expression))	CTD
caffeine	MGST1	Text_Mining(decreases(expression))	CTD
caffeine	MICB	Text_Mining(decreases(methylation))	CTD
caffeine	MICB	Text_Mining(decreases(reaction))	CTD
caffeine	MICB	Text_Mining(increases(expression))	CTD
caffeine	MT1G	Text_Mining(increases(expression))	CTD
caffeine	MTOR	Text_Mining(decreases(activity))	CTD
caffeine	NAT2	Text_Mining(affects(metabolic processing))	CTD
caffeine	NAT2	Text_Mining(increases(acetylation))	CTD
caffeine	OAT	Text_Mining(increases(expression))	CTD
caffeine	PAK2	Text_Mining(increases(activity))	CTD
caffeine	PARP1	Text_Mining(affects(cleavage))	CTD
caffeine	PARP1	Text_Mining(affects(cotreatment))	CTD
caffeine	PARP1	Text_Mining(increases(activity))	CTD
caffeine	PARP1	Text_Mining(increases(cleavage))	CTD
caffeine	PARP1	Text_Mining(increases(reaction))	CTD
caffeine	PARP1	Text_Mining(increases(expression))	CTD
caffeine	PLP1	Text_Mining(increases(expression))	CTD
caffeine	PPP2R2B	Text_Mining(decreases(expression))	CTD
caffeine	PRELID1	Text_Mining(decreases(expression))	CTD
caffeine	PRKDC	Text_Mining(increases(activity))	CTD
caffeine	PRKDC	Text_Mining(increases(phosphorylation))	CTD
caffeine	PRKDC	Text_Mining(increases(reaction))	CTD
caffeine	PRNP	Text_Mining(decreases(expression))	CTD
caffeine	PSME3	Text_Mining(decreases(expression))	CTD
caffeine	PTGS2	Text_Mining(decreases(expression))	CTD
caffeine	RB1	Text_Mining(decreases(phosphorylation))	CTD
caffeine	REN	Text_Mining(increases(activity))	CTD
caffeine	RPS6	Text_Mining(decreases(expression))	CTD
caffeine	RPS6KA3	Text_Mining(decreases(expression))	CTD
caffeine	RPS6KB1	Text_Mining(decreases(expression))	CTD
caffeine	RRS1	Text_Mining(increases(expression))	CTD
caffeine	RYR1	Text_Mining(increases(activity))	CTD
caffeine	RYR1	Text_Mining(affects(localization))	CTD
caffeine	RYR1	Text_Mining(increases(response to substance))	CTD
caffeine	RYR1	Text_Mining(affects(reaction))	CTD
caffeine	RYR1	Text_Mining(increases(secretion))	CTD
caffeine	SCFD1	Text_Mining(decreases(expression))	CTD
caffeine	SEC13	Text_Mining(decreases(expression))	CTD
caffeine	SEC23A	Text_Mining(decreases(expression))	CTD
caffeine	SERPINA1	Text_Mining(increases(expression))	CTD
caffeine	SERPINA6	Text_Mining(decreases(expression))	CTD
caffeine	SLC16A1	Text_Mining(affects(reaction))	CTD
caffeine	SLC16A1	Text_Mining(increases(uptake))	CTD
caffeine	SLC16A1	Text_Mining(increases(expression))	CTD
caffeine	SMOX	Text_Mining(increases(expression))	CTD
caffeine	SQLE	Text_Mining(decreases(expression))	CTD
caffeine	SQSTM1	Text_Mining(decreases(reaction))	CTD
caffeine	SQSTM1	Text_Mining(increases(degradation))	CTD
caffeine	SQSTM1	Text_Mining(decreases(expression))	CTD
caffeine	SRSF1	Text_Mining(decreases(expression))	CTD
caffeine	STAR	Text_Mining(decreases(methylation))	CTD
caffeine	STAR	Text_Mining(increases(expression))	CTD
caffeine	STRBP	Text_Mining(decreases(expression))	CTD
caffeine	TFDP1	Text_Mining(decreases(expression))	CTD
caffeine	TM9SF1	Text_Mining(decreases(expression))	CTD
caffeine	TMCC2	Text_Mining(increases(expression))	CTD
caffeine	TMEM97	Text_Mining(decreases(expression))	CTD
caffeine	TNFSF4	Text_Mining(increases(expression))	CTD
caffeine	TP53	Text_Mining(decreases(reaction))	CTD
caffeine	TP53	Text_Mining(increases(phosphorylation))	CTD
caffeine	TP53	Text_Mining(increases(expression))	CTD
caffeine	TP53	Text_Mining(increases(activity))	CTD
caffeine	TXNRD1	Text_Mining(decreases(expression))	CTD
caffeine	UGT1A1	Text_Mining(increases(expression))	CTD
caffeine	UQCRC2	Text_Mining(decreases(expression))	CTD
caffeine	XDH	Text_Mining(affects(metabolic processing))	CTD
caffeine	YWHAQ	Text_Mining(affects(binding))	CTD
caffeine	YWHAQ	Text_Mining(decreases(reaction))	CTD
caffeine	ZNF37A	Text_Mining(increases(expression))	CTD
caffeine	AR	Potency-Replicate_1=49.1509(uM)	D4 PubChem
caffeine	CYP1A2	Inhibition=None(Unspecified)	D4 ChEMBL
caffeine	CYP2C19	Inhibition=None(Unspecified)	D4 ChEMBL
caffeine	CYP2C9	Inhibition=None(Unspecified)	D4 ChEMBL
caffeine	CYP2D6	Inhibition=None(Unspecified)	D4 ChEMBL
caffeine	CYP3A4	Inhibition=None(Unspecified)	D4 ChEMBL
caffeine	NFE2L2	Ratio Potency (uM)=8.09465(uM)	D4 PubChem