Drug Gene Type Source buprenorphine CYP2C8 Text_Mining(affects(metabolic processing)) CTD buprenorphine CYP2D6 Text_Mining(decreases(activity)) CTD buprenorphine CYP2D6 Text_Mining(increases(metabolic processing)) CTD buprenorphine CYP3A4 Text_Mining(decreases(activity)) CTD buprenorphine CYP3A4 Text_Mining(affects(metabolic processing)) CTD buprenorphine CYP3A4 Text_Mining(decreases(alkylation)) CTD buprenorphine CYP3A4 Text_Mining(increases(metabolic processing)) CTD buprenorphine IL2 Text_Mining(decreases(expression)) CTD buprenorphine IL4 Text_Mining(increases(expression)) CTD buprenorphine MAPK1 Text_Mining(increases(phosphorylation)) CTD buprenorphine MAPK3 Text_Mining(increases(phosphorylation)) CTD buprenorphine OPRD1 Text_Mining(affects(binding)) CTD buprenorphine OPRD1 Text_Mining(decreases(reaction)) CTD buprenorphine OPRK1 Text_Mining(affects(binding)) CTD buprenorphine OPRK1 Text_Mining(decreases(reaction)) CTD buprenorphine OPRL1 Text_Mining(affects(binding)) CTD buprenorphine OPRL1 Text_Mining(increases(activity)) CTD buprenorphine OPRM1 Text_Mining(affects(activity)) CTD buprenorphine OPRM1 Text_Mining(affects(binding)) CTD buprenorphine OPRM1 Text_Mining(increases(activity)) CTD buprenorphine OPRM1 Text_Mining(decreases(reaction)) CTD buprenorphine UGT1A1 Text_Mining(increases(glucuronidation)) CTD