Drug Gene Type Source azathioprine ABCB1 Text_Mining(affects(response to substance)) CTD azathioprine AKT1 Text_Mining(decreases(reaction)) CTD azathioprine AKT1 Text_Mining(increases(phosphorylation)) CTD azathioprine BCL2L1 Text_Mining(decreases(expression)) CTD azathioprine DPP4 Text_Mining(decreases(expression)) CTD azathioprine FOS Text_Mining(increases(expression)) CTD azathioprine FOXO1 Text_Mining(decreases(reaction)) CTD azathioprine FOXO1 Text_Mining(increases(phosphorylation)) CTD azathioprine GCLM Text_Mining(increases(expression)) CTD azathioprine GPX2 Text_Mining(increases(expression)) CTD azathioprine GPX3 Text_Mining(increases(expression)) CTD azathioprine GSS Text_Mining(increases(expression)) CTD azathioprine GSTA1 Text_Mining(affects(metabolic processing)) CTD azathioprine GSTA2 Text_Mining(affects(response to substance)) CTD azathioprine GSTA2 Text_Mining(affects(metabolic processing)) CTD azathioprine GSTM1 Text_Mining(affects(response to substance)) CTD azathioprine GSTM1 Text_Mining(affects(metabolic processing)) CTD azathioprine HLA-DQA1 Text_Mining(affects(response to substance)) CTD azathioprine HLA-DRB1 Text_Mining(affects(response to substance)) CTD azathioprine IGF1 Text_Mining(decreases(reaction)) CTD azathioprine IGF1 Text_Mining(increases(phosphorylation)) CTD azathioprine IGF1R Text_Mining(decreases(reaction)) CTD azathioprine IGF1R Text_Mining(increases(phosphorylation)) CTD azathioprine IGF1R Text_Mining(decreases(expression)) CTD azathioprine IL12A Text_Mining(affects(binding)) CTD azathioprine IL12A Text_Mining(increases(expression)) CTD azathioprine IL12B Text_Mining(affects(binding)) CTD azathioprine IL12B Text_Mining(increases(expression)) CTD azathioprine IL1A Text_Mining(affects(cotreatment)) CTD azathioprine IL1A Text_Mining(increases(response to substance)) CTD azathioprine IL4 Text_Mining(decreases(expression)) CTD azathioprine IL6 Text_Mining(affects(cotreatment)) CTD azathioprine IL6 Text_Mining(increases(response to substance)) CTD azathioprine IMPDH1 Text_Mining(affects(response to substance)) CTD azathioprine IMPDH2 Text_Mining(increases(expression)) CTD azathioprine IRS1 Text_Mining(decreases(expression)) CTD azathioprine IRS1 Text_Mining(increases(phosphorylation)) CTD azathioprine ITPA Text_Mining(affects(response to substance)) CTD azathioprine JUN Text_Mining(increases(expression)) CTD azathioprine MAP2K1 Text_Mining(decreases(phosphorylation)) CTD azathioprine MAPK1 Text_Mining(affects(binding)) CTD azathioprine MAPK1 Text_Mining(decreases(reaction)) CTD azathioprine MAPK1 Text_Mining(increases(reaction)) CTD azathioprine MAPK1 Text_Mining(increases(phosphorylation)) CTD azathioprine MAPK3 Text_Mining(affects(binding)) CTD azathioprine MAPK3 Text_Mining(decreases(reaction)) CTD azathioprine MAPK3 Text_Mining(increases(reaction)) CTD azathioprine MAPK3 Text_Mining(increases(phosphorylation)) CTD azathioprine MTOR Text_Mining(increases(phosphorylation)) CTD azathioprine PTCH1 Text_Mining(affects(mutagenesis)) CTD azathioprine RAC1 Text_Mining(affects(binding)) CTD azathioprine RAC1 Text_Mining(decreases(reaction)) CTD azathioprine RAC1 Text_Mining(decreases(activity)) CTD azathioprine RAC1 Text_Mining(affects(response to substance)) CTD azathioprine RPS6KB1 Text_Mining(decreases(reaction)) CTD azathioprine RPS6KB1 Text_Mining(increases(phosphorylation)) CTD azathioprine SLC15A1 Text_Mining(decreases(expression)) CTD azathioprine SOD2 Text_Mining(increases(expression)) CTD azathioprine STAT3 Text_Mining(affects(binding)) CTD azathioprine STAT3 Text_Mining(decreases(reaction)) CTD azathioprine TNF Text_Mining(increases(expression)) CTD azathioprine TNF Text_Mining(affects(cotreatment)) CTD azathioprine TNF Text_Mining(increases(response to substance)) CTD azathioprine TP53 Text_Mining(increases(expression)) CTD azathioprine TP53 Text_Mining(increases(mutagenesis)) CTD azathioprine TPMT Text_Mining(affects(activity)) CTD azathioprine TPMT Text_Mining(affects(response to substance)) CTD azathioprine TPMT Text_Mining(affects(metabolic processing)) CTD azathioprine TSC2 Text_Mining(affects(binding)) CTD azathioprine TSC2 Text_Mining(decreases(reaction)) CTD azathioprine TSC2 Text_Mining(increases(reaction)) CTD azathioprine VAV1 Text_Mining(increases(expression)) CTD azathioprine ABCB1 None=None(uM) D4 PubChem azathioprine AHR AhR Potency (uM)=22.5529(uM) D4 PubChem azathioprine AHR Potency-Replicate_1=27.1395(uM) D4 PubChem azathioprine ATAD5 Potency=0.2059(uM) D4 PubChem azathioprine ATAD5 Potency=205.9(nM) D4 ChEMBL azathioprine CYP1A2 Inhibition=None(Unspecified) D4 ChEMBL azathioprine CYP2C19 Inhibition=None(Unspecified) D4 ChEMBL azathioprine CYP2C9 Inhibition=None(Unspecified) D4 ChEMBL azathioprine CYP2D6 Inhibition=None(Unspecified) D4 ChEMBL azathioprine CYP3A4 Inhibition=None(Unspecified) D4 ChEMBL azathioprine HBB Potency=0.3162(uM) D4 PubChem azathioprine HBB Potency=1.5849(uM) D4 PubChem azathioprine HBB Potency=1.99526(uM) D4 PubChem azathioprine HBB Potency=2.5119(uM) D4 PubChem azathioprine HBB Potency=1995.26(nM) D4 ChEMBL azathioprine HBB Potency=1584.9(nM) D4 ChEMBL azathioprine HBB Potency=2511.9(nM) D4 ChEMBL azathioprine HBB Potency=316.2(nM) D4 ChEMBL azathioprine IDH1 Potency=4.1095(uM) D4 PubChem azathioprine JAK2 None=None(uM) D4 PubChem azathioprine NFE2L2 Ratio Potency (uM)=7.52192(uM) D4 PubChem azathioprine NFE2L2 Potency-Replicate_1=8.412(uM) D4 PubChem azathioprine NFE2L2 Ratio Potency (uM)=10.1914(uM) D4 PubChem azathioprine NFE2L2 Potency=27.306(uM) D4 PubChem azathioprine NFE2L2 Potency=37.578(uM) D4 PubChem azathioprine STK33 None=None(uM) D4 PubChem azathioprine TNFRSF10B None=None(uM) D4 PubChem