Drug Gene Type Source kaempferol ABCB1 Text_Mining(increases(transport)) CTD kaempferol ABCB1 Text_Mining(decreases(reaction)) CTD kaempferol ABCB1 Text_Mining(increases(secretion)) CTD kaempferol ABCC1 Text_Mining(affects(activity)) CTD kaempferol ABCC1 Text_Mining(decreases(activity)) CTD kaempferol AHR Text_Mining(affects(binding)) CTD kaempferol AHR Text_Mining(decreases(reaction)) CTD kaempferol AHR Text_Mining(increases(activity)) CTD kaempferol AHR Text_Mining(increases(reaction)) CTD kaempferol AHR Text_Mining(increases(phosphorylation)) CTD kaempferol AKT1 Text_Mining(decreases(reaction)) CTD kaempferol AKT1 Text_Mining(increases(phosphorylation)) CTD kaempferol ALOX12 Text_Mining(decreases(reaction)) CTD kaempferol ALOX12 Text_Mining(increases(chemical synthesis)) CTD kaempferol ALOX12 Text_Mining(decreases(activity)) CTD kaempferol ARNT Text_Mining(affects(binding)) CTD kaempferol ARNT Text_Mining(decreases(reaction)) CTD kaempferol ARNT Text_Mining(increases(reaction)) CTD kaempferol ARNT Text_Mining(increases(phosphorylation)) CTD kaempferol ATM Text_Mining(decreases(reaction)) CTD kaempferol ATM Text_Mining(increases(phosphorylation)) CTD kaempferol B3GALT5 Text_Mining(decreases(expression)) CTD kaempferol BAX Text_Mining(increases(expression)) CTD kaempferol BBC3 Text_Mining(decreases(reaction)) CTD kaempferol BBC3 Text_Mining(increases(expression)) CTD kaempferol BBC3 Text_Mining(affects(binding)) CTD kaempferol BBC3 Text_Mining(increases(reaction)) CTD kaempferol BBC3 Text_Mining(affects(reaction)) CTD kaempferol BCL2 Text_Mining(decreases(expression)) CTD kaempferol BCL2L1 Text_Mining(affects(binding)) CTD kaempferol BCL2L1 Text_Mining(increases(reaction)) CTD kaempferol BCL2L1 Text_Mining(affects(reaction)) CTD kaempferol CASP3 Text_Mining(increases(cleavage)) CTD kaempferol CASP9 Text_Mining(increases(cleavage)) CTD kaempferol CCL5 Text_Mining(affects(cotreatment)) CTD kaempferol CCL5 Text_Mining(decreases(expression)) CTD kaempferol CCNB1 Text_Mining(decreases(expression)) CTD kaempferol CDK1 Text_Mining(decreases(activity)) CTD kaempferol CDK1 Text_Mining(increases(phosphorylation)) CTD kaempferol CDKN1A Text_Mining(increases(expression)) CTD kaempferol CDKN2C Text_Mining(decreases(expression)) CTD kaempferol CFTR Text_Mining(affects(localization)) CTD kaempferol CHUK Text_Mining(decreases(phosphorylation)) CTD kaempferol CRP Text_Mining(decreases(expression)) CTD kaempferol CSF2 Text_Mining(decreases(reaction)) CTD kaempferol CSF2 Text_Mining(increases(secretion)) CTD kaempferol CYCS Text_Mining(affects(localization)) CTD kaempferol CYCS Text_Mining(decreases(reaction)) CTD kaempferol CYP1A1 Text_Mining(decreases(reaction)) CTD kaempferol CYP1A1 Text_Mining(increases(activity)) CTD kaempferol CYP1A1 Text_Mining(increases(expression)) CTD kaempferol CYP1A1 Text_Mining(affects(binding)) CTD kaempferol CYP1A1 Text_Mining(increases(reaction)) CTD kaempferol CYP1A1 Text_Mining(decreases(activity)) CTD kaempferol CYP1A1 Text_Mining(affects(activity)) CTD kaempferol CYP1A1 Text_Mining(affects(cotreatment)) CTD kaempferol CYP1A2 Text_Mining(decreases(reaction)) CTD kaempferol CYP1A2 Text_Mining(increases(expression)) CTD kaempferol CYP1A2 Text_Mining(decreases(activity)) CTD kaempferol CYP1B1 Text_Mining(affects(binding)) CTD kaempferol CYP1B1 Text_Mining(decreases(activity)) CTD kaempferol CYP1B1 Text_Mining(decreases(reaction)) CTD kaempferol CYP1B1 Text_Mining(increases(reaction)) CTD kaempferol CYP1B1 Text_Mining(increases(expression)) CTD kaempferol CYP1B1 Text_Mining(decreases(expression)) CTD kaempferol CYP2C9 Text_Mining(decreases(reaction)) CTD kaempferol CYP2C9 Text_Mining(increases(hydroxylation)) CTD kaempferol CYP3A4 Text_Mining(decreases(reaction)) CTD kaempferol CYP3A4 Text_Mining(increases(degradation)) CTD kaempferol CYP3A4 Text_Mining(decreases(activity)) CTD kaempferol CYP3A4 Text_Mining(increases(expression)) CTD kaempferol DIO2 Text_Mining(increases(abundance)) CTD kaempferol DIO2 Text_Mining(increases(activity)) CTD kaempferol DIO2 Text_Mining(increases(reaction)) CTD kaempferol DIO2 Text_Mining(increases(expression)) CTD kaempferol ESR1 Text_Mining(decreases(reaction)) CTD kaempferol ESR1 Text_Mining(increases(expression)) CTD kaempferol ESR1 Text_Mining(affects(reaction)) CTD kaempferol ESR1 Text_Mining(increases(activity)) CTD kaempferol ESR1 Text_Mining(affects(binding)) CTD kaempferol ESR1 Text_Mining(increases(reaction)) CTD kaempferol ESR1 Text_Mining(increases(localization)) CTD kaempferol ESR2 Text_Mining(affects(reaction)) CTD kaempferol ESR2 Text_Mining(increases(activity)) CTD kaempferol ESR2 Text_Mining(affects(binding)) CTD kaempferol ESR2 Text_Mining(decreases(reaction)) CTD kaempferol FBP1 Text_Mining(decreases(expression)) CTD kaempferol FOS Text_Mining(affects(binding)) CTD kaempferol FOS Text_Mining(decreases(reaction)) CTD kaempferol FOS Text_Mining(increases(activity)) CTD kaempferol GADD45B Text_Mining(increases(expression)) CTD kaempferol GCLC Text_Mining(increases(expression)) CTD kaempferol GREB1 Text_Mining(decreases(reaction)) CTD kaempferol GREB1 Text_Mining(increases(expression)) CTD kaempferol GREB1 Text_Mining(affects(binding)) CTD kaempferol GREB1 Text_Mining(increases(reaction)) CTD kaempferol GSTA1 Text_Mining(increases(expression)) CTD kaempferol GSTP1 Text_Mining(decreases(activity)) CTD kaempferol H2AFX Text_Mining(increases(phosphorylation)) CTD kaempferol HBB Text_Mining(decreases(reaction)) CTD kaempferol HBB Text_Mining(increases(response to substance)) CTD kaempferol HGF Text_Mining(decreases(reaction)) CTD kaempferol HGF Text_Mining(increases(phosphorylation)) CTD kaempferol ICAM1 Text_Mining(decreases(reaction)) CTD kaempferol ICAM1 Text_Mining(increases(expression)) CTD kaempferol IL1B Text_Mining(decreases(reaction)) CTD kaempferol IL1B Text_Mining(increases(expression)) CTD kaempferol IL1B Text_Mining(increases(phosphorylation)) CTD kaempferol IL4 Text_Mining(decreases(reaction)) CTD kaempferol IL4 Text_Mining(increases(expression)) CTD kaempferol IL5 Text_Mining(decreases(reaction)) CTD kaempferol IL5 Text_Mining(increases(expression)) CTD kaempferol IL5 Text_Mining(affects(cotreatment)) CTD kaempferol IL5 Text_Mining(decreases(expression)) CTD kaempferol IL6 Text_Mining(affects(cotreatment)) CTD kaempferol IL6 Text_Mining(decreases(expression)) CTD kaempferol JUN Text_Mining(affects(binding)) CTD kaempferol JUN Text_Mining(decreases(reaction)) CTD kaempferol JUN Text_Mining(increases(activity)) CTD kaempferol JUN Text_Mining(increases(expression)) CTD kaempferol KMT2A Text_Mining(increases(mutagenesis)) CTD kaempferol MAPK1 Text_Mining(decreases(reaction)) CTD kaempferol MAPK1 Text_Mining(increases(phosphorylation)) CTD kaempferol MAPK3 Text_Mining(decreases(reaction)) CTD kaempferol MAPK3 Text_Mining(increases(phosphorylation)) CTD kaempferol MET Text_Mining(decreases(reaction)) CTD kaempferol MET Text_Mining(increases(phosphorylation)) CTD kaempferol MT2A Text_Mining(increases(expression)) CTD kaempferol MUC5AC Text_Mining(decreases(reaction)) CTD kaempferol MUC5AC Text_Mining(increases(expression)) CTD kaempferol NCOA3 Text_Mining(affects(binding)) CTD kaempferol NCOA3 Text_Mining(increases(reaction)) CTD kaempferol NFE2L2 Text_Mining(decreases(reaction)) CTD kaempferol NFE2L2 Text_Mining(increases(expression)) CTD kaempferol NFKBIA Text_Mining(decreases(phosphorylation)) CTD kaempferol NOS2 Text_Mining(decreases(expression)) CTD kaempferol NR1I2 Text_Mining(increases(activity)) CTD kaempferol NR1I3 Text_Mining(increases(activity)) CTD kaempferol PGR Text_Mining(decreases(reaction)) CTD kaempferol PGR Text_Mining(increases(expression)) CTD kaempferol PGR Text_Mining(affects(binding)) CTD kaempferol POU5F1 Text_Mining(decreases(expression)) CTD kaempferol PPARGC1A Text_Mining(increases(expression)) CTD kaempferol PSCA Text_Mining(decreases(expression)) CTD kaempferol PTGS2 Text_Mining(decreases(reaction)) CTD kaempferol PTGS2 Text_Mining(increases(expression)) CTD kaempferol PTGS2 Text_Mining(decreases(expression)) CTD kaempferol RPA3 Text_Mining(affects(cotreatment)) CTD kaempferol RPA3 Text_Mining(increases(expression)) CTD kaempferol SFN Text_Mining(increases(expression)) CTD kaempferol SLC2A1 Text_Mining(affects(transport)) CTD kaempferol SLC2A1 Text_Mining(decreases(reaction)) CTD kaempferol SLC2A1 Text_Mining(decreases(activity)) CTD kaempferol STAT2 Text_Mining(affects(cotreatment)) CTD kaempferol STAT2 Text_Mining(decreases(expression)) CTD kaempferol TFAM Text_Mining(increases(expression)) CTD kaempferol TFF1 Text_Mining(decreases(reaction)) CTD kaempferol TFF1 Text_Mining(increases(expression)) CTD kaempferol TGFA Text_Mining(decreases(reaction)) CTD kaempferol TGFA Text_Mining(increases(expression)) CTD kaempferol TNF Text_Mining(affects(binding)) CTD kaempferol TNF Text_Mining(decreases(reaction)) CTD kaempferol TNF Text_Mining(increases(activity)) CTD kaempferol TNF Text_Mining(increases(expression)) CTD kaempferol TP53 Text_Mining(decreases(reaction)) CTD kaempferol TP53 Text_Mining(increases(phosphorylation)) CTD kaempferol TP53 Text_Mining(increases(expression)) CTD kaempferol TP53 Text_Mining(affects(binding)) CTD kaempferol TP53 Text_Mining(affects(reaction)) CTD kaempferol TP53 Text_Mining(increases(reaction)) CTD kaempferol TP53 Text_Mining(affects(response to substance)) CTD kaempferol TP53I3 Text_Mining(increases(expression)) CTD kaempferol TP63 Text_Mining(increases(expression)) CTD kaempferol TP73 Text_Mining(increases(expression)) CTD kaempferol UCP3 Text_Mining(increases(expression)) CTD kaempferol UGT1A1 Text_Mining(increases(glucuronidation)) CTD kaempferol UGT1A10 Text_Mining(increases(glucuronidation)) CTD kaempferol UGT1A3 Text_Mining(affects(glucuronidation)) CTD kaempferol UGT1A3 Text_Mining(increases(glucuronidation)) CTD kaempferol UGT1A7 Text_Mining(increases(glucuronidation)) CTD kaempferol UGT1A8 Text_Mining(increases(glucuronidation)) CTD kaempferol UGT1A9 Text_Mining(increases(glucuronidation)) CTD kaempferol UTRN Text_Mining(increases(expression)) CTD kaempferol WISP2 Text_Mining(decreases(reaction)) CTD kaempferol WISP2 Text_Mining(increases(expression)) CTD kaempferol ADAM10 None=None(uM) D4 PubChem kaempferol ADAM17 None=None(uM) D4 PubChem kaempferol AHR AhR Potency (uM)=30.5133(uM) D4 PubChem kaempferol AHR AhR Potency (uM)=44.5532(uM) D4 PubChem kaempferol AR Ratio Potency (uM)=26.4083(uM) D4 PubChem kaempferol CHRM1 None=None(uM) D4 PubChem kaempferol CTDSP1 IC50=9.933(uM) D4 PubChem kaempferol CTDSP1 None=None(uM) D4 PubChem kaempferol CYP19A1 None=None(uM) D4 PubChem kaempferol CYP1A2 None=None(uM) D4 PubChem kaempferol CYP1A2 AC50=79.43(nM) D4 ChEMBL kaempferol CYP2C9 Potency=15.8489(uM) D4 PubChem kaempferol CYP2C9 Potency=15848.9(nM) D4 ChEMBL kaempferol CYP2D6 Potency=10.0(uM) D4 PubChem kaempferol CYP2D6 Potency=15.8489(uM) D4 PubChem kaempferol CYP2D6 None=None(uM) D4 PubChem kaempferol CYP2D6 Potency=10000.0(nM) D4 ChEMBL kaempferol CYP2D6 AC50=10000.0(nM) D4 ChEMBL kaempferol CYP2D6 Potency=15848.9(nM) D4 ChEMBL kaempferol CYP3A4 Potency=15.8489(uM) D4 PubChem kaempferol CYP3A4 Potency=15848.9(nM) D4 ChEMBL kaempferol ESR1 Potency=7.9433(uM) D4 PubChem kaempferol ESR1 Potency=8.9125(uM) D4 PubChem kaempferol ESR1 Potency-Replicate_1=18.4309(uM) D4 PubChem kaempferol ESR1 Potency-Replicate_1=21.7975(uM) D4 PubChem kaempferol ESR1 Ratio Potency (uM)=21.7975(uM) D4 PubChem kaempferol ESR1 Potency-Replicate_1=24.2376(uM) D4 PubChem kaempferol ESR1 Potency-Replicate_1=26.2643(uM) D4 PubChem kaempferol ESR1 Potency-Replicate_1=27.4414(uM) D4 PubChem kaempferol ESR1 Ratio Potency (uM)=33.0402(uM) D4 PubChem kaempferol ESR1 Ratio Potency (uM)=33.246(uM) D4 PubChem kaempferol GSK3B EC50_uM=11.59(uM) D4 PubChem kaempferol HIF1A Potency=1.5849(uM) D4 PubChem kaempferol HIF1A Potency=1584.9(nM) D4 ChEMBL kaempferol HPGD Potency=28.1838(uM) D4 PubChem kaempferol HPGD Potency=28183.8(nM) D4 ChEMBL kaempferol HSD17B10 Potency=15848.9(nM) D4 ChEMBL kaempferol MAPT Potency=12.5893(uM) D4 PubChem kaempferol MAPT None=None(uM) D4 PubChem kaempferol MAPT Potency=12589.3(nM) D4 ChEMBL kaempferol NFE2L2 Potency=21.6899(uM) D4 PubChem kaempferol NR1I2 Potency-Replicate_1=44.6684(uM) D4 PubChem kaempferol NR3C1 None=None(uM) D4 PubChem kaempferol PAFAH1B3 None=None(uM) D4 PubChem kaempferol PIM2 None=None(uM) D4 PubChem kaempferol POLH Potency=25.1189(uM) D4 PubChem kaempferol POLI Potency=79.4328(uM) D4 PubChem kaempferol PPARG Ratio Potency (uM)=None(uM) D4 PubChem kaempferol RACGAP1 IC50=44.49(uM) D4 PubChem kaempferol STK16 None=None(uM) D4 PubChem