Drug Gene Type Source Sphingosine 1-phosphate AKT1 Text_Mining(increases(activity)) CTD Sphingosine 1-phosphate AKT1 Text_Mining(increases(phosphorylation)) CTD Sphingosine 1-phosphate CREB1 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate CREB1 Text_Mining(increases(phosphorylation)) CTD Sphingosine 1-phosphate CXCL8 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate CXCL8 Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate CXCR1 Text_Mining(decreases(expression)) CTD Sphingosine 1-phosphate CYP17A1 Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate HGF Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate IGF1 Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate KDR Text_Mining(decreases(expression)) CTD Sphingosine 1-phosphate KDR Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate LAMA3 Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate LAMB3 Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate LAMC2 Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate MAPK1 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate MAPK1 Text_Mining(increases(phosphorylation)) CTD Sphingosine 1-phosphate MAPK1 Text_Mining(increases(activity)) CTD Sphingosine 1-phosphate MAPK3 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate MAPK3 Text_Mining(increases(phosphorylation)) CTD Sphingosine 1-phosphate MAPK3 Text_Mining(increases(activity)) CTD Sphingosine 1-phosphate NRP1 Text_Mining(decreases(expression)) CTD Sphingosine 1-phosphate NRP1 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate NRP2 Text_Mining(decreases(expression)) CTD Sphingosine 1-phosphate NRP2 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate PTGS2 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate PTGS2 Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate PTGS2 Text_Mining(increases(reaction)) CTD Sphingosine 1-phosphate S1PR2 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate S1PR2 Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate S1PR3 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate S1PR3 Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate SMPD2 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate SMPD2 Text_Mining(increases(activity)) CTD Sphingosine 1-phosphate SPHK1 Text_Mining(increases(chemical synthesis)) CTD Sphingosine 1-phosphate TNF Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate TNF Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate VCAM1 Text_Mining(decreases(reaction)) CTD Sphingosine 1-phosphate VCAM1 Text_Mining(increases(expression)) CTD Sphingosine 1-phosphate GNAI1 None=None(uM) D4 PubChem Sphingosine 1-phosphate RGS12 None=None(uM) D4 PubChem Sphingosine 1-phosphate S1PR1 Activity=None(Unspecified) D4 ChEMBL Sphingosine 1-phosphate S1PR1 Inhibition=None(Unspecified) D4 ChEMBL