Drug Gene Type Source topiramate CA1 Text_Mining(affects(binding)) CTD topiramate CA1 Text_Mining(decreases(activity)) CTD topiramate CA12 Text_Mining(decreases(activity)) CTD topiramate CA2 Text_Mining(affects(binding)) CTD topiramate CA2 Text_Mining(decreases(activity)) CTD topiramate CA3 Text_Mining(affects(binding)) CTD topiramate CA3 Text_Mining(decreases(activity)) CTD topiramate CYP17A1 Text_Mining(decreases(activity)) CTD topiramate CYP3A4 Text_Mining(increases(activity)) CTD topiramate CYP3A4 Text_Mining(increases(expression)) CTD topiramate GRIK1 Text_Mining(affects(response to substance)) CTD topiramate HSD3B2 Text_Mining(decreases(activity)) CTD topiramate KCNH2 Text_Mining(decreases(activity)) CTD topiramate NR1I2 Text_Mining(increases(activity)) CTD topiramate UGT2B7 Text_Mining(affects(response to substance)) CTD topiramate AQP4 Activity=None(Unspecified) D4 ChEMBL