Drug Gene Type Source butein AKT1 Text_Mining(decreases(phosphorylation)) CTD butein DIO2 Text_Mining(decreases(activity)) CTD butein HMOX1 Text_Mining(decreases(reaction)) CTD butein HMOX1 Text_Mining(increases(expression)) CTD butein HMOX1 Text_Mining(increases(activity)) CTD butein HMOX1 Text_Mining(increases(abundance)) CTD butein HMOX1 Text_Mining(decreases(response to substance)) CTD butein HMOX1 Text_Mining(decreases(activity)) CTD butein HMOX1 Text_Mining(decreases(expression)) CTD butein MMP9 Text_Mining(decreases(expression)) CTD butein MMP9 Text_Mining(increases(reaction)) CTD butein MMP9 Text_Mining(decreases(reaction)) CTD butein MMP9 Text_Mining(increases(expression)) CTD butein NFE2L2 Text_Mining(affects(localization)) CTD butein NFKB1 Text_Mining(affects(localization)) CTD butein RELA Text_Mining(affects(localization)) CTD butein SIRT1 Text_Mining(increases(activity)) CTD butein TNF Text_Mining(decreases(reaction)) CTD butein TNF Text_Mining(increases(expression)) CTD butein VEGFA Text_Mining(decreases(expression)) CTD butein POLK Potency=21.1923(uM) D4 PubChem