Drug	Gene	Type	Source
leflunomide	TNF	Text_Mining(PMID22389919,PMID23024081,PMID21904814,PMID22370803,PMID20190998,PMID20191470,PMID22301842,PMID23926075,PMID20398005,PMID22121511,PMID20032102,PMID21794814,PMID20448284,PMID22383918,PMID20455343,PMID20412708,PMID21985166,PMID20532787,PMID22563027,PMID22563027,PMID25046427,PMID24611179,PMID20097592,PMID24193188,PMID24782683,PMID24204948,PMID21630616,PMID22772888,PMID23032984,PMID20798949,PMID22073935,PMID22073935,PMID24401994)	BOSS
leflunomide	DHODH	Text_Mining(PMID21109332,PMID22966891,PMID21355448,PMID21686163,PMID23682862,PMID20413687,PMID21962758,PMID19751817,PMID21430780,PMID22245049,PMID23143678,PMID21157651,PMID21845515,PMID24566615,PMID24189582,PMID23944378,PMID20489727,PMID21861807,PMID22052286,PMID22072733,PMID24746616,PMID23977077,PMID22580100,PMID22580100,PMID22784880)	BOSS
leflunomide	IL6	Text_Mining(PMID24432685,PMID24432685,PMID20398005,PMID22245957,PMID22870474,PMID23114585,PMID24255778,PMID24782683,PMID24204948,PMID22073935)	BOSS
leflunomide	MTX1	Text_Mining(PMID24489150,PMID21794790,PMID20082236,PMID24387970,PMID21044434,PMID24677947,PMID23997576,PMID24231065)	BOSS
leflunomide	ACR	Text_Mining(PMID23918169,PMID22763150,PMID21794790,PMID20082236,PMID23223695,PMID24193188,PMID24231065)	BOSS
leflunomide	PITX1	Text_Mining(PMID22639744,PMID21803751,PMID23968502,PMID24106691,PMID20412708,PMID24677820,PMID24480317)	BOSS
leflunomide	CYP2C8	Text_Mining(PMID23447478,PMID22879383,PMID22879383,PMID22784880,PMID22784880,PMID22784880,PMID22784880)	BOSS
leflunomide	IL4	Text_Mining(PMID22414257,PMID20506498,PMID20506498,PMID22563027,PMID24708771,PMID22072733,PMID22072733)	BOSS
leflunomide	EREG	Text_Mining(PMID22639744,PMID24164840,PMID21803751,PMID21174621,PMID20412708,PMID24677820)	BOSS
leflunomide	MTR	Text_Mining(PMID23682862,PMID21157651,PMID21367665,PMID23944378,PMID23695001,PMID22052286)	BOSS
leflunomide	AHR	Text_Mining(PMID22242167,PMID23100028,PMID20957046,PMID22815870,PMID22879383,PMID25011475)	BOSS
leflunomide	ABCG2	Text_Mining(PMID20972558,PMID23711386,PMID23447478,PMID22784880,PMID22784880)	BOSS
leflunomide	ALB	Text_Mining(PMID20650041,PMID22243699,PMID23726631,PMID22371643,PMID20648003)	BOSS
leflunomide	NFKB2	Text_Mining(PMID19912216,PMID21845515,PMID22243699,PMID19770782,PMID22749778)	BOSS
leflunomide	MMP9	Text_Mining(PMID24124747,PMID24124747,PMID21871883,PMID22749778,PMID25011475)	BOSS
leflunomide	IL27	Text_Mining(PMID24432685,PMID23626769,PMID23334376,PMID24123677,PMID22749778)	BOSS
leflunomide	CD4	Text_Mining(PMID22057872,PMID20689824,PMID20130738,PMID22563027,PMID24677872,PMID)	BOSS
leflunomide	AHR	AhR Potency (uM)=1.01235(uM)	D4 PubChem
leflunomide	AHR	Potency-Replicate_1=1.1359(uM)	D4 PubChem
leflunomide	AHR	AhR Potency (uM)=6.60073(uM)	D4 PubChem
leflunomide	AHR	Potency-Replicate_1=21.6899(uM)	D4 PubChem
leflunomide	AHR	None=None(uM)	D4 PubChem
leflunomide	ATAD5	Potency=2.0588(uM)	D4 PubChem
leflunomide	ATAD5	Potency=2058.8(nM)	D4 ChEMBL
leflunomide	CASP3	None=None(uM)	D4 PubChem
leflunomide	CYP1A2	None=None(uM)	D4 PubChem
leflunomide	CYP1A2	AC50=63.1(nM)	D4 ChEMBL
leflunomide	CYP3A4	Potency=0.631(uM)	D4 PubChem
leflunomide	CYP3A4	Potency=5.0119(uM)	D4 PubChem
leflunomide	CYP3A4	None=None(uM)	D4 PubChem
leflunomide	CYP3A4	AC50=5011.87(nM)	D4 ChEMBL
leflunomide	CYP3A4	Potency=631.0(nM)	D4 ChEMBL
leflunomide	CYP3A4	Potency=5011.9(nM)	D4 ChEMBL
leflunomide	DHODH	Inhibition=None(Unspecified)	D4 ChEMBL
leflunomide	DRD1	None=None(uM)	D4 PubChem
leflunomide	DRD2	None=None(uM)	D4 PubChem
leflunomide	HSPB1	Ratio Potency (uM)=19.4938(uM)	D4 PubChem
leflunomide	HTT	Potency=0.3162(uM)	D4 PubChem
leflunomide	HTT	Potency=316.2(nM)	D4 ChEMBL
leflunomide	MMP14	EC50=5.65(uM)	D4 PubChem
leflunomide	NFE2L2	Ratio Potency (uM)=20.4766(uM)	D4 PubChem
leflunomide	NFE2L2	Potency-Replicate_1=30.6379(uM)	D4 PubChem
leflunomide	NR0B1	None=None(uM)	D4 PubChem
leflunomide	RAB9A	Potency=1.4125(uM)	D4 PubChem
leflunomide	RAB9A	Potency=1412.5(nM)	D4 ChEMBL
leflunomide	SENP6	None=None(uM)	D4 PubChem
leflunomide	SENP7	None=None(uM)	D4 PubChem
leflunomide	SENP8	None=None(uM)	D4 PubChem
leflunomide	SMN1; SMN2	Potency=15848.9(nM)	D4 ChEMBL
leflunomide	SMN1; SMN2	Potency=14125.4(nM)	D4 ChEMBL
leflunomide	SMN1; SMN2	Potency=7079.5(nM)	D4 ChEMBL
leflunomide	SMN1; SMN2	Potency=11220.2(nM)	D4 ChEMBL
leflunomide	SMN1; SMN2	Potency=17782.8(nM)	D4 ChEMBL
leflunomide	SMN2	Potency=7.0795(uM)	D4 PubChem
leflunomide	SMN2	Potency=11.2202(uM)	D4 PubChem
leflunomide	SMN2	Potency=14.1254(uM)	D4 PubChem
leflunomide	SMN2	Potency=15.8489(uM)	D4 PubChem
leflunomide	SMN2	Potency=17.7828(uM)	D4 PubChem
leflunomide	TDP1	Potency=1.0137(uM)	D4 PubChem
leflunomide	TDP1	Potency=4.6109(uM)	D4 PubChem
leflunomide	TDP1	Potency=7.3078(uM)	D4 PubChem
leflunomide	TDP1	Potency=9.2(uM)	D4 PubChem