Drug	Gene	Type	Source
Orphenadrine hydrochloride	AKR1B1	Text_Mining(PMID23268781,PMID23380161,PMID20430028,PMID23738366,PMID22428303,PMID22951468,PMID19940435,PMID20064212,PMID20461579,PMID22057031,PMID22546276,PMID21620918,PMID22276587,PMID21605098,PMID20684324,PMID21771269,PMID21946153,PMID24013142,PMID19799905,PMID23792627,PMID21846805,PMID23284852,PMID23954394,PMID23838629,PMID21069171,PMID20598360,PMID21315100,PMID20878947,PMID23023563,PMID23415714,PMID23415714,PMID21766324,PMID21592171,PMID22402471,PMID24726995,PMID24293191,PMID24293191,PMID22553513,PMID20641097,PMID20689246,PMID20682842,PMID19790238,PMID24528975,PMID24887087,PMID19901962,PMID23546600,PMID24151599,PMID20108248,PMID24066237,PMID18440837,PMID22661176,PMID22661176,PMID20709035,PMID20709035,PMID22956306,PMID21840325,PMID22405892,PMID22152882,PMID21839661,PMID21903763,PMID22525094,PMID23301637,PMID22567171,PMID23782943,PMID23801677,PMID24754006,PMID19714448,PMID21126777,PMID24742193,PMID24323721,PMID24469767,PMID20961723,PMID23123233,PMID21843721,PMID21338237,PMID20719434,PMID20821602,PMID21342526,PMID23365095,PMID20850791,PMID20353424,PMID23401794,PMID23340667,PMID24248458,PMID23284699,PMID23707571,PMID24362045,PMID24453069,PMID24782426,PMID20392832,PMID20048160,PMID21290409,PMID22177695,PMID20211643,PMID22445695,PMID22047186,PMID22556124,PMID22366056,PMID22009729,PMID21664964,PMID21965742,PMID21812788,PMID22150386,PMID22019845,PMID20399256,PMID20332615,PMID20541672,PMID22807478,PMID21876548,PMID22219300,PMID19787772,PMID22234368,PMID22309306,PMID22309306,PMID21521268,PMID21036174,PMID22935919,PMID23885104,PMID19766145,PMID19660519,PMID20580788,PMID21374593,PMID22093481,PMID21185853,PMID21281786,PMID21130428,PMID24784499,PMID21418339,PMID24902786,PMID24512496,PMID22430536,PMID24169563,PMID23895735,PMID24604890,PMID20338164,PMID24642882,PMID25031707,PMID20573408,PMID20207835,PMID23316499,PMID23316499,PMID21457548,PMID23816265,PMID23816265,PMID20154177,PMID20337887,PMID22002493,PMID24282438,PMID24799026,PMID19836445,PMID20442653,PMID19833195,PMID22307005,PMID21894443,PMID23869618,PMID22533969,PMID20043082,PMID23130941,PMID23216709,PMID21439799,PMID24658017,PMID24140269,PMID20609311,PMID24055403,PMID22449547,PMID22323373,PMID20954080,PMID23399021,PMID24773946,PMID23467324,PMID20482693,PMID21856600,PMID21111724)	BOSS
Orphenadrine hydrochloride	C7orf49	Text_Mining(PMID20236639,PMID21455837,PMID21818942,PMID20336287,PMID23710187,PMID22253665,PMID24582157,PMID20665894,PMID21825013,PMID21052633,PMID21696428,PMID23378873,PMID24662905,PMID23677122,PMID23886750,PMID23703539,PMID21071481,PMID22258654,PMID22471262,PMID21412783,PMID21538197,PMID20306980,PMID20605292,PMID20655016,PMID23494851,PMID23604791,PMID22334461,PMID23345486,PMID22798724,PMID23612911,PMID24462185,PMID24620309,PMID21484690,PMID23381299,PMID21039796,PMID21261025,PMID24946359,PMID23181771,PMID24977064,PMID24562874,PMID24685124,PMID21288962,PMID22980765,PMID22639740,PMID21842297,PMID22076979,PMID20575296,PMID24616743,PMID20537927,PMID21276556,PMID22534512,PMID20173152,PMID24323445,PMID23113529,PMID22790805,PMID24658615,PMID21048389,PMID20966327,PMID24369412,PMID21436160,PMID24514010,PMID22407628,PMID22884222,PMID21547883,PMID22121126,PMID23729806,PMID20235485,PMID24677820,PMID23961495)	BOSS
Orphenadrine hydrochloride	RYR1	Text_Mining(PMID20692880,PMID22249494,PMID20959112,PMID24638093,PMID22891308,PMID22891308,PMID21840325,PMID20443062,PMID20443062,PMID24950660,PMID24950660,PMID24950660,PMID24950660,PMID21262876,PMID20686070,PMID20961389,PMID20961389,PMID23152933,PMID23152933,PMID22139840,PMID22139840,PMID20837675,PMID22802359,PMID21289290,PMID21289290,PMID21149547,PMID21149547,PMID21149547,PMID21156754,PMID21156754,PMID24004537,PMID24004537)	BOSS
Orphenadrine hydrochloride	GCK	Text_Mining(PMID22386416,PMID19594741,PMID20947624,PMID23774685,PMID24870772,PMID20421544,PMID21128595,PMID21795830,PMID22493411,PMID21440505,PMID20807265,PMID22503022,PMID23872177,PMID23739989,PMID22907511,PMID23444510,PMID21965742,PMID20541672,PMID22180287,PMID20202011,PMID22420486,PMID22574096,PMID21867542,PMID21867542,PMID24807533,PMID21111724)	BOSS
Orphenadrine hydrochloride	NLN	Text_Mining(PMID22837166,PMID23478202,PMID22596357,PMID24388283,PMID21408031,PMID21406217,PMID20730420,PMID23806753,PMID23366771,PMID24671544,PMID21160006,PMID20414558,PMID22791231,PMID21088609,PMID22434254,PMID21606110,PMID21672559,PMID25007330,PMID21258930,PMID20457734,PMID20881507,PMID23867064,PMID21861922,PMID22323647,PMID20363183)	BOSS
Orphenadrine hydrochloride	IGFBP1	Text_Mining(PMID21961641,PMID21946153,PMID20522734,PMID22773197,PMID22773197,PMID22930413,PMID21839661,PMID22286428,PMID24578521,PMID20961723,PMID20961723,PMID21338237,PMID21338237,PMID23284699,PMID23284699,PMID22935919,PMID24429066,PMID21246620)	BOSS
Orphenadrine hydrochloride	ESR1	Text_Mining(PMID21766324,PMID22152882,PMID20605569,PMID21843721,PMID21189209,PMID24453069,PMID20048160,PMID22807478,PMID22234368,PMID21185853,PMID24902786,PMID23220561,PMID24055403,PMID22323373,PMID20954080,PMID25011475,PMID24037977)	BOSS
Orphenadrine hydrochloride	TNF	Text_Mining(PMID23580948,PMID23580948,PMID22776879,PMID19640554,PMID23056540,PMID23182229,PMID24156755,PMID21430397,PMID21430397,PMID24006180,PMID24512496,PMID20458732,PMID21706829,PMID21706829,PMID21677888)	BOSS
Orphenadrine hydrochloride	INS	Text_Mining(PMID21741799,PMID22930413,PMID22454153,PMID21785444,PMID20064856,PMID21521268,PMID19687797,PMID24889738,PMID20844264,PMID21894443,PMID24807533,PMID24840528,PMID23247555,PMID20500100,PMID21865363)	BOSS
Orphenadrine hydrochloride	IL6	Text_Mining(PMID24022572,PMID24022572,PMID24966805,PMID21180882,PMID21180882,PMID24833277,PMID22776879,PMID23056540,PMID24006180,PMID23451164,PMID23451164,PMID24015193,PMID23266138)	BOSS
Orphenadrine hydrochloride	PLXNA3	Text_Mining(PMID21160000,PMID22708113,PMID25090008,PMID23514703,PMID22747582,PMID22585552,PMID23249767,PMID24802858,PMID20962189,PMID22820064,PMID21512399,PMID21522693,PMID21050966)	BOSS
Orphenadrine hydrochloride	GJA1	Text_Mining(PMID20558338,PMID20558338,PMID23571006,PMID23571006,PMID19853283,PMID19853283,PMID21457361,PMID24151599,PMID24151599,PMID20961722,PMID20961722,PMID21342526,PMID21342526)	BOSS
Orphenadrine hydrochloride	BPNT1	Text_Mining(PMID22292317,PMID21282212,PMID21469183,PMID23942817,PMID23617293,PMID22647791,PMID21725663,PMID24426678,PMID23475135,PMID21883842,PMID21883842,PMID24341058)	BOSS
Orphenadrine hydrochloride	LDHA	Text_Mining(PMID24164218,PMID23620988,PMID24195702,PMID24195702,PMID20175712,PMID20175712,PMID24012702,PMID21059078,PMID24282438,PMID19836445,PMID20500100,PMID23266138)	BOSS
Orphenadrine hydrochloride	PRPH	Text_Mining(PMID21075372,PMID23413856,PMID22903286,PMID21813313,PMID21538197,PMID21365335,PMID24249539,PMID21725663,PMID21842297,PMID23352184,PMID24054350)	BOSS
Orphenadrine hydrochloride	CYP2C8	Text_Mining(PMID21203749,PMID22009729,PMID23043943,PMID24353261,PMID20417212,PMID21130428,PMID20456834,PMID20456834,PMID22879383,PMID22879383,PMID22076107)	BOSS
Orphenadrine hydrochloride	ACLY	Text_Mining(PMID21298255,PMID23510376,PMID21667178,PMID21846002,PMID23612067,PMID20591177,PMID22543515,PMID23835518,PMID23595537,PMID23217112,PMID24453613)	BOSS
Orphenadrine hydrochloride	CTGF	Text_Mining(PMID23056540,PMID22675458,PMID22675458,PMID20458732,PMID20458732,PMID20337887,PMID20337887,PMID20337887,PMID19743505,PMID24015193)	BOSS
Orphenadrine hydrochloride	CACNA1S	Text_Mining(PMID21715697,PMID24806927,PMID21078869,PMID21262876,PMID24282497,PMID23821476,PMID23321639,PMID20837675,PMID23869618,PMID21439799)	BOSS
Orphenadrine hydrochloride	COL9A2	Text_Mining(PMID21077920,PMID23320252,PMID21061159,PMID22893604,PMID20943434,PMID20043789,PMID23906005,PMID23032594,PMID20830455,PMID20830455)	BOSS
Orphenadrine hydrochloride	PRL	Text_Mining(PMID24615730,PMID23885104,PMID22078782,PMID22078782,PMID23220561,PMID24909896,PMID24211351,PMID23506438,PMID21856600)	BOSS
Orphenadrine hydrochloride	PVALB	Text_Mining(PMID20689450,PMID20393069,PMID21530674,PMID19997852,PMID23950168,PMID23182229,PMID23284699,PMID21446356,PMID24365365)	BOSS
Orphenadrine hydrochloride	ACOX2	Text_Mining(PMID23197549,PMID20052570,PMID22653906,PMID23692210,PMID24528975,PMID20702801,PMID21855918,PMID24714718,PMID22560514)	BOSS
Orphenadrine hydrochloride	MTR	Text_Mining(PMID22612360,PMID20512584,PMID21148266,PMID20457538,PMID22562952,PMID23867064,PMID23949051,PMID23634192,PMID23365095)	BOSS
Orphenadrine hydrochloride	MAPK3	Text_Mining(PMID23429276,PMID23801677,PMID22019845,PMID19660519,PMID21374593,PMID21480798,PMID20442653,PMID20609311,PMID24773946)	BOSS
Orphenadrine hydrochloride	HBB	Text_Mining(PMID22894482,PMID23471683,PMID22854253,PMID21559872,PMID20379830,PMID23332345,PMID23747168,PMID23399021,PMID24365365)	BOSS
Orphenadrine hydrochloride	BCL2	Text_Mining(PMID21638510,PMID22209211,PMID21549119,PMID20117302,PMID20850791,PMID20353424,PMID24793618,PMID24658017)	BOSS
Orphenadrine hydrochloride	SOD1	Text_Mining(PMID24175124,PMID22521362,PMID24037920,PMID22277500,PMID20235485,PMID22078782,PMID21443684,PMID21443684)	BOSS
Orphenadrine hydrochloride	ROCK1	Text_Mining(PMID20064212,PMID21210624,PMID20704113,PMID20485034,PMID20135975,PMID20135975,PMID20359757,PMID20207835)	BOSS
Orphenadrine hydrochloride	SLC25A20	Text_Mining(PMID20069312,PMID20837639,PMID24744863,PMID21262876,PMID20399256,PMID20351595,PMID24004537,PMID24807533)	BOSS
Orphenadrine hydrochloride	FBXW4	Text_Mining(PMID22207054,PMID25064964,PMID22813719,PMID22415931,PMID22446520,PMID20542992,PMID24125761,PMID24464802)	BOSS
Orphenadrine hydrochloride	OTOR	Text_Mining(PMID22883898,PMID20427405,PMID21561624,PMID23219762,PMID22398793,PMID22714687,PMID23670492,PMID24341058)	BOSS
Orphenadrine hydrochloride	IL1B	Text_Mining(PMID23056540,PMID23182229,PMID23182229,PMID24156755,PMID22384219,PMID20337887,PMID19743505,PMID24055403)	BOSS
Orphenadrine hydrochloride	PRG4	Text_Mining(PMID23389791,PMID20516321,PMID24906811,PMID24445876,PMID23335124,PMID22561248,PMID24349551,PMID22714687)	BOSS
Orphenadrine hydrochloride	IGLL2P	Text_Mining(PMID23302746,PMID22366254,PMID23386748,PMID22460474,PMID24944855,PMID21733463,PMID23182012)	BOSS
Orphenadrine hydrochloride	ATP8A2	Text_Mining(PMID24022572,PMID20049087,PMID21849670,PMID24282497,PMID23321639,PMID21059078,PMID24349043)	BOSS
Orphenadrine hydrochloride	CASP3	Text_Mining(PMID22525094,PMID21530649,PMID22567171,PMID23872177,PMID24658017,PMID20609311,PMID24773946)	BOSS
Orphenadrine hydrochloride	CYGB	Text_Mining(PMID24429677,PMID20088676,PMID23043943,PMID22002493,PMID23665939,PMID23665940,PMID22076107)	BOSS
Orphenadrine hydrochloride	AHI1	Text_Mining(PMID21576719,PMID21282212,PMID21469183,PMID22647791,PMID21725663,PMID24426678,PMID24341058)	BOSS
Orphenadrine hydrochloride	GDF5	Text_Mining(PMID21436509,PMID21282221,PMID24812579,PMID24812579,PMID22792383,PMID21050966,PMID21050966)	BOSS
Orphenadrine hydrochloride	ABCA1	Text_Mining(PMID24383888,PMID22556124,PMID19660519,PMID20442653,PMID20442653,PMID20609311,PMID24773946)	BOSS
Orphenadrine hydrochloride	FGF13	Text_Mining(PMID21601885,PMID20926722,PMID21683624,PMID21625055,PMID21735786,PMID22811469)	BOSS
Orphenadrine hydrochloride	EREG	Text_Mining(PMID20598360,PMID20951417,PMID20821602,PMID21048389,PMID21876548,PMID24677820)	BOSS
Orphenadrine hydrochloride	CSH1	Text_Mining(PMID24878271,PMID23683374,PMID20702801,PMID22773197,PMID20593204,PMID22648949)	BOSS
Orphenadrine hydrochloride	DCN	Text_Mining(PMID23941206,PMID21928430,PMID24571598,PMID23251524,PMID20830455,PMID22882155)	BOSS
Orphenadrine hydrochloride	MMP9	Text_Mining(PMID22792383,PMID21222132,PMID21222132,PMID20842701,PMID23775880,PMID25011475)	BOSS
Orphenadrine hydrochloride	PAF1	Text_Mining(PMID20558338,PMID24151599,PMID21342526,PMID22177695,PMID21812788,PMID24353261)	BOSS
Orphenadrine hydrochloride	NLK	Text_Mining(PMID23762501,PMID23941206,PMID24571598,PMID23251524,PMID22241901,PMID22882155)	BOSS
Orphenadrine hydrochloride	ACP2	Text_Mining(PMID22843430,PMID23735314,PMID22675458,PMID22675458,PMID23586515,PMID24015193)	BOSS
Orphenadrine hydrochloride	FN1	Text_Mining(PMID20652877,PMID22095400,PMID19757183,PMID21851252,PMID23586515,PMID23251524)	BOSS
Orphenadrine hydrochloride	FAM109A	Text_Mining(PMID22446520,PMID20542992,PMID24464802,PMID24464802,PMID24464802)	BOSS
Orphenadrine hydrochloride	ATP1B1	Text_Mining(PMID22653906,PMID24164218,PMID21840325,PMID21486400,PMID23869618)	BOSS
Orphenadrine hydrochloride	CYP2B6	Text_Mining(PMID20088676,PMID20088676,PMID20417212,PMID20580788,PMID23665939)	BOSS
Orphenadrine hydrochloride	IGLL1	Text_Mining(PMID20551285,PMID24643099,PMID23291080,PMID24342500,PMID20831388)	BOSS
Orphenadrine hydrochloride	DDR2	Text_Mining(PMID24742292,PMID21126777,PMID23038006,PMID22566500,PMID24909896)	BOSS
Orphenadrine hydrochloride	TTR	Text_Mining(PMID22037778,PMID22606333,PMID19205710,PMID20610052,PMID21334722)	BOSS
Orphenadrine hydrochloride	HSD17B1	Text_Mining(PMID20032741,PMID24568944,PMID24303814,PMID24303814,PMID23130941)	BOSS
Orphenadrine hydrochloride	CD44	Text_Mining(PMID20438995,PMID19757183,PMID21851252,PMID20154177,PMID24965110)	BOSS
Orphenadrine hydrochloride	CDH2	Text_Mining(PMID23580948,PMID21812788,PMID24353261,PMID24353261,PMID24784499,PMID)	BOSS
Orphenadrine hydrochloride	CHRM4	None=None(uM)	D4 PubChem
Orphenadrine hydrochloride	CHRM5	None=None(uM)	D4 PubChem
Orphenadrine hydrochloride	DRD3	None=None(uM)	D4 PubChem
Orphenadrine hydrochloride	KCNH2	Potency=8.9125(uM)	D4 PubChem
Orphenadrine hydrochloride	NR1I2	Potency-Replicate_1=44.6684(uM)	D4 PubChem