Drug Gene Type Source mitotane SLC6A2 IC50=0.819(uM) D1 PubChem mitotane SLC6A3 IC50=1.001(uM) D1 PubChem mitotane HTR6 IC50=1.402(uM) D1 PubChem mitotane SLC6A4 IC50=3.015(uM) D1 PubChem mitotane HTR2B IC50=4.832(uM) D1 PubChem mitotane KCNH2 Potency=5.6234(uM) D1 PubChem mitotane ESR1 Potency=6.0012(uM) D1 PubChem mitotane ADRA2A IC50=7.347(uM) D1 PubChem mitotane ADORA3 IC50=7.445(uM) D1 PubChem mitotane ESR1 Ratio Potency (uM)=7.55501(uM) D1 PubChem mitotane ESR1 Potency=7.6959(uM) D1 PubChem mitotane ESR1 Potency=8.4127(uM) D1 PubChem mitotane NR3C1 Potency=10.6822(uM) D1 PubChem mitotane ESR1 Ratio Potency (uM)=13.8039(uM) D1 PubChem mitotane NR3C1 Potency=27.5391(uM) D1 PubChem mitotane ATM Potency=28.1838(uM) D1 PubChem mitotane NR1I2 Potency=31.6228(uM) D1 PubChem mitotane KCNH2 Potency=31.6228(uM) D1 PubChem mitotane RORC Potency=33.4915(uM) D1 PubChem mitotane ESR1 Potency=48.9722(uM) D1 PubChem mitotane NFE2L2 Potency=66.8242(uM) D1 PubChem mitotane TP53 Potency=68.5896(uM) D1 PubChem mitotane NR3C1 - D1 PubChem mitotane KCNK3 - D1 PubChem mitotane ARNT - D1 PubChem mitotane TACC3 - D1 PubChem mitotane CYP11A1 - D1 PubChem mitotane CYP11B1 - D1 PubChem mitotane KCNH2 Potency=31622.8(nM) D1 ChEMBL mitotane KCNH2 Potency=5623.4(nM) D1 ChEMBL mitotane RORC Potency=33491.5(nM) D1 ChEMBL mitotane NFE2L2 Potency=66824.2(nM) D1 ChEMBL mitotane ATM Potency=28183.8(nM) D1 ChEMBL